UCHL5 — MultiTargetDB

Target Details

UniProt AC	`Q9Y5K5`
Gene Symbol	UCHL5
Protein Name	Ubiquitin carboxyl-terminal hydrolase isozyme L5
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF01088 (Peptidase_C12) PF18031 (UCH_C)

Summary

Multi-target molecules 146
Clinical molecules 144
Avg pChEMBL 7.11

KEGG Pathways (1)

ATP-dependent chromatin remodeling

Top Co-occurrence Targets

GABRB1 144 shared
SLC6A4 51 shared
HRH3 48 shared
SLC6A2 7 shared
SLC6A3 5 shared
KCNH2 3 shared
ADRA2A 3 shared
SUPT16H 2 shared
EIF3L 2 shared
ZMYND8 2 shared

Active Molecules (146)

InChIKey	pChEMBL	Type	Targets	Clinical
`MWKSRKSEWLRPBL`	7.2	Kd	1075	—
`AAAQFGUYHFJNHI`	7.0	IC50	252	—
`ACRVFRPOWNWNAQ`	Clinical	TTD_MultiTarget	2	Yes
`AGFIIERRTNLUMS`	Clinical	TTD_MultiTarget	4	Yes
`AHOJZWPBIHIALS`	Clinical	TTD_MultiTarget	4	Yes
`AJXWEERKJZAIJJ`	Clinical	TTD_MultiTarget	2	Yes
`ALZTYVXVRZIERJ`	Clinical	TTD_MultiTarget	2	Yes
`AUMQJULFKZREJZ`	Clinical	TTD_MultiTarget	2	Yes
`BDHLYFHGXMWWJR`	Clinical	TTD_MultiTarget	4	Yes
`BDWXFGZMHKOMCV`	Clinical	TTD_MultiTarget	4	Yes
`BJWZNXSSJMLUNB`	Clinical	TTD_MultiTarget	4	Yes
`BQBXKSFQNZVIMG`	Clinical	TTD_MultiTarget	4	Yes
`BSDHAHZVUCTDKG`	Clinical	TTD_MultiTarget	2	Yes
`CAISPEIKDAWTHS`	Clinical	TTD_MultiTarget	7	Yes
`CCXHRSBOCZSERO`	Clinical	TTD_MultiTarget	2	Yes
`CEQAEEYYVALJJW`	Clinical	TTD_MultiTarget	4	Yes
`CKIBSEDGQQBNJP`	Clinical	TTD_MultiTarget	2	Yes
`CPILYYRWNUVSHU`	Clinical	TTD_MultiTarget	2	Yes
`CPVIJSYBBQJOPU`	Clinical	TTD_MultiTarget	2	Yes
`CQWSBUJEGUSBFA`	Clinical	TTD_MultiTarget	2	Yes
`CRUWXQPBIKVAJO`	Clinical	TTD_MultiTarget	2	Yes
`CWKGVKHDADMKBI`	Clinical	TTD_MultiTarget	2	Yes
`DCFPUUCKXNHIPZ`	Clinical	TTD_MultiTarget	2	Yes
`DGCHOADTPWCGNV`	Clinical	TTD_MultiTarget	2	Yes
`DIMAAAZZSSXDEH`	Clinical	TTD_MultiTarget	4	Yes
`DTDLOHYXZTWBHO`	Clinical	TTD_MultiTarget	2	Yes
`DTYOTXLNOUBXKR`	Clinical	TTD_MultiTarget	2	Yes
`DUKRHXPXPYNWKN`	Clinical	TTD_MultiTarget	4	Yes
`DYUSEVKSEDICGM`	Clinical	TTD_MultiTarget	6	Yes
`DZMTUSAQZVLLBN`	Clinical	TTD_MultiTarget	2	Yes
`FINNTOGAVZWNGL`	Clinical	TTD_MultiTarget	2	Yes
`FJWNUBKVWQZAGY`	Clinical	TTD_MultiTarget	4	Yes
`FJZUSTRVJVXQSY`	Clinical	TTD_MultiTarget	2	Yes
`FLLOSWVXSHXQDY`	Clinical	TTD_MultiTarget	2	Yes
`FLZMPXADQFZKGE`	Clinical	TTD_MultiTarget	2	Yes
`FWJKAQILVAFVQQ`	Clinical	TTD_MultiTarget	6	Yes
`FYQWSOGFMUPHGU`	Clinical	TTD_MultiTarget	2	Yes
`GMAJNYRLILNPJN`	Clinical	TTD_MultiTarget	2	Yes
`GQEPEMYIRJCODM`	Clinical	TTD_MultiTarget	2	Yes
`GTLCRPKCYIDHGJ`	Clinical	TTD_MultiTarget	4	Yes
`HAOCEOSCGBBHFB`	Clinical	TTD_MultiTarget	4	Yes
`HAZUWABOLNYYCL`	Clinical	TTD_MultiTarget	4	Yes
`HFOWUCXCCMJFIB`	Clinical	TTD_MultiTarget	2	Yes
`HRDUUEDPDCVSJF`	Clinical	TTD_MultiTarget	2	Yes
`HVNNDZMWORMJPO`	Clinical	TTD_MultiTarget	2	Yes
`HXRQPFYBNJXVTR`	Clinical	TTD_MultiTarget	2	Yes
`IBDXBPHXQDUOAO`	Clinical	TTD_MultiTarget	2	Yes
`IHQGRRRYHOHPFV`	Clinical	TTD_MultiTarget	2	Yes
`INWLSQYDDFJBQN`	Clinical	TTD_MultiTarget	2	Yes
`IUSJINNBGHLFTG`	Clinical	TTD_MultiTarget	2	Yes