Target Details
| UniProt AC | Q9UP38 |
|---|---|
| Gene Symbol | FZD1 |
| Protein Name | Frizzled-1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01534 (Frizzled) PF01392 (Fz) |
Summary
- Multi-target molecules 4
- Clinical molecules 0
- Avg pChEMBL 9.01
KEGG Pathways (16)
- Alzheimer disease
- Basal cell carcinoma
- Breast cancer
- Cadherin signaling
- Cushing syndrome
- Gastric cancer
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human papillomavirus infection
- Melanogenesis
- Pathways in cancer
- Pathways of neurodegeneration - multiple diseases
- Proteoglycans in cancer
- Signaling pathways regulating pluripotency of stem cells
- Wnt signaling pathway
- mTOR signaling pathway
Active Molecules (4)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RSJXDEAMGGTCOH
|
9.5 | Kd | 2 | — | |
LBSJIZBYRZVTNK
|
9.0 | IC50 | 2 | — | |
KSVDFWYEBGERRY
|
9.0 | Kd | 2 | — | |
OVZPTLAZBWGCER
|
8.6 | Kd | 2 | — |