Target Details
UniProt ACQ9UHI8
Gene SymbolADAMTS1
Protein NameA disintegrin and metalloproteinase with thrombospondin motifs 1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF17771 (ADAMTS_CR_2) PF19236 (ADAMTS_CR_3) PF05986 (ADAMTS_spacer1) PF01562 (Pep_M12B_propep) PF01421 (Reprolysin) PF19030 (TSP1_ADAMTS) PF00090 (TSP_1)
Summary
  • Multi-target molecules 6
  • Clinical molecules 2
  • Avg pChEMBL 6.76
Top Co-occurrence Targets
Active Molecules (6)
InChIKey pChEMBL Type Targets Clinical
ZRQWUQCXSKEXGA 7.5 Ki 6
GNBHJTYIJMLFLC 7.2 Ki 6
LTVIJEFEZVFIST 7.1 IC50 14 Yes
SZEOXTMGYZKQHV 6.5 IC50 4
PWTMEJOXAUSTDY 6.2 IC50 4
BODLESUVCQEUII 6.1 Ki 7 Yes
2D structure