Target Details
UniProt ACQ9NZ42
Gene SymbolPSENEN
Protein NameGamma-secretase subunit PEN-2
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF10251 (PEN-2)
UniProt
Summary
  • Multi-target molecules 1,927
  • Clinical molecules 1
  • Avg pChEMBL 7.37
KEGG Pathways (3)
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (1,927)
InChIKey pChEMBL Type Targets Clinical
OSNMZQWHTIACIS 7.2 IC50 6 —
PVYMEWFIIZLAAI 7.2 IC50 6 —
WXPYBMGDQFAXLV 7.2 IC50 6 —
AXCVMFAXSHQHGD 7.2 IC50 6 —
BXMBAARDPRZROY 7.2 IC50 6 —
OXDRUSUGTYNQAM 7.2 IC50 6 —
QFIYDPSUTMHADW 7.2 IC50 6 —
RPHWSLBXUOMLGT 7.2 IC50 6 —
FDDILKPZEYSVMW 7.2 IC50 6 —
IBVIPCHEAYMOIU 7.2 IC50 6 —
JEYWVZNITKXMAA 7.2 IC50 6 —
QFTDBTQRSJWLDN 7.2 IC50 6 —
RYKZGRFQSYQWNX 7.2 IC50 6 —
YQXKNZRDPZBYEE 7.2 IC50 6 —
ZSERTYLZGRJLOO 7.2 IC50 6 —
BXQJZJQFDUGDQE 7.2 IC50 6 —
GMNQLLUODIGEJV 7.2 IC50 6 —
GMNQLLUODIGEJV 7.2 IC50 6 —
HMEXKVHGQGUAHM 7.2 IC50 6 —
JKETUMKQLRSDFG 7.2 IC50 6 —
OABVPHMXGVFMQT 7.2 IC50 6 —
OHXQPMCUJTWQJA 7.2 IC50 6 —
OLTJQPQTIFFPOR 7.2 IC50 6 —
OYSWPIMRDJSCJW 7.2 IC50 6 —
RLLAQGUARIWLLV 7.2 IC50 6 —
SHPWXEFRRYKBDM 7.2 IC50 6 —
SKDXSNNSZNFGGJ 7.2 IC50 6 —
UBWCFTVMEDMMPH 7.2 IC50 6 —
UOTIXMXOYZCICU 7.2 IC50 6 —
FMMQURLBVRREQY 7.2 IC50 6 —
GSJRIJNVASEMGE 7.2 IC50 6 —
HDZRQPPPUOILEX 7.2 IC50 6 —
HRCNMOLPDBROLW 7.2 IC50 6 —
PMTRKYRHVQKGGU 7.2 IC50 6 —
QLZIPZSSIJMSKJ 7.2 IC50 6 —
SWOZAFWHDLVMNG 7.2 IC50 6 —
UDIQMHOHOCRKGM 7.2 IC50 7 —
XATMGDHWHJHERK 7.2 IC50 6 —
DJABFSKRSPBFDM 7.1 IC50 6 —
HBGLAAUAIUPMON 7.1 IC50 6 —
HZSIJLACSNPTDP 7.1 IC50 6 —
KDOWJBVDWWLMPX 7.1 IC50 6 —
LJIUZNSCZLHTFT 7.1 IC50 6 —
LZSBLSJQJHXKLB 7.1 IC50 6 —
MEIBAUIZWBBTLF 7.1 IC50 6 —
MURCDOXDAHPNRQ 7.1 IC50 8 —
NFCYCVSTJIQVSU 7.1 IC50 6 —
NFZWXCQYERVPEI 7.1 IC50 6 —
NONHWESJQFIAJQ 7.1 IC50 6 —
SEMGDCNPEKJXOY 7.1 IC50 6 —
2D structure