Target Details
UniProt ACQ9NZ42
Gene SymbolPSENEN
Protein NameGamma-secretase subunit PEN-2
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF10251 (PEN-2)
UniProt
Summary
  • Multi-target molecules 1,927
  • Clinical molecules 1
  • Avg pChEMBL 7.37
KEGG Pathways (3)
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (1,927)
InChIKey pChEMBL Type Targets Clinical
XPGMDHBMKACPGG 7.2 IC50 6 —
ZBQSQLZJIGVCBL 7.2 IC50 7 —
DQLVLNIXRNYZNK 7.2 IC50 6 —
FPVPTAAXBAUXGB 7.2 IC50 6 —
HTPYICLKDABRCS 7.2 IC50 6 —
OUEPYXLGBQMEPH 7.2 IC50 6 —
SBJYGLWYBXZUAW 7.2 IC50 6 —
VMZLVFQTRRZQRG 7.2 IC50 6 —
XSLNGFKYBKVQSF 7.2 IC50 6 —
YRNULWHSWZKWLM 7.2 IC50 6 —
ZDQMWYMKIJGJNB 7.2 IC50 6 —
FQFIYJTUQGASOC 7.2 IC50 6 —
FUIQEFAUOQZFBZ 7.2 IC50 6 —
JPFIVLHIBZXRKR 7.2 IC50 6 —
LLMJHJOMFAYVAN 7.2 IC50 6 —
PFHPUQTYKDOHGM 7.2 IC50 6 —
TZCXHOJPNBMDIP 7.2 IC50 6 —
VZFDGCDPRGKJRJ 7.2 IC50 6 —
WHQMAYDRXHCVRM 7.2 IC50 6 —
WKBVYYOKXHXPSV 7.2 IC50 6 —
XZGMRTZEDNSSBH 7.2 IC50 6 —
DIGSRNGZVYWJEK 7.2 IC50 6 —
DIGSRNGZVYWJEK 7.2 IC50 6 —
HIXFEPNWHKYAGE 7.2 IC50 6 —
LLPXEFMTHNCKNM 7.2 IC50 6 —
NVRPIFOUCJMRHX 7.2 IC50 6 —
OORQWZXKRAWRSB 7.2 IC50 6 —
RCTIQFHQOVGEJY 7.2 IC50 6 —
UVHVYGYHHUQZQQ 7.2 IC50 6 —
VXERYLRQRKSKHH 7.2 IC50 6 —
WTAHCIYSWXNHHD 7.2 IC50 6 —
YHAMQGANHLKCMN 7.2 IC50 6 —
AAHNBILIYONQLX 7.2 IC50 13 —
AAHNBILIYONQLX 7.2 IC50 7 —
CYOIIUJMQAMQCE 7.2 IC50 6 —
DINAVFJXFRFCRE 7.2 IC50 6 —
FLWYMPRMOKCVLR 7.2 IC50 6 —
IUKNHXHAYIPWCO 7.2 IC50 6 —
NORCRZDORGFXKI 7.2 IC50 6 —
PAINQWCUWYGDLM 7.2 IC50 6 —
UIDMHMNKHAKPDY 7.2 IC50 6 —
VPTWIQNXYBDCCO 7.2 IC50 6 —
ZCEYBHZDTMQCMM 7.2 IC50 6 —
ZTHMSKAZMYITIW 7.2 IC50 6 —
AAUYNLNUWXYMOX 7.2 IC50 6 —
FNGBGXPVVBCEGE 7.2 IC50 6 —
FTHWMXAAFNYFAB 7.2 IC50 6 —
GYAZOBIEKWKUTN 7.2 IC50 6 —
ONYWALXTZFPKAS 7.2 IC50 6 —
OPBCSQTYQHKIFO 7.2 IC50 8 —
2D structure