Target Details
| UniProt AC | Q9NZ42 |
|---|---|
| Gene Symbol | PSENEN |
| Protein Name | Gamma-secretase subunit PEN-2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF10251 (PEN-2) |
Summary
- Multi-target molecules 1,927
- Clinical molecules 1
- Avg pChEMBL 7.37
KEGG Pathways (3)
Associated Diseases (1)
Active Molecules (1,927)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
DDQNBVZKZXCOQE
|
7.8 | IC50 | 6 | — | |
LNEQSINHSHRPJR
|
7.8 | IC50 | 6 | — | |
LTKKMSORNDRROD
|
7.8 | IC50 | 7 | — | |
ODEIUBHPOCSQNG
|
7.8 | IC50 | 6 | — | |
ORAIOKXZWONRGK
|
7.8 | IC50 | 6 | — | |
PDOHVGKIOMMAAD
|
7.8 | IC50 | 6 | — | |
REGUKWPDBFIQSN
|
7.8 | IC50 | 6 | — | |
SVZUXFAZHKXJHN
|
7.8 | IC50 | 6 | — | |
XHCUZDCYMWAJBU
|
7.8 | IC50 | 6 | — | |
ZQYDYFCAHHBFKE
|
7.8 | IC50 | 6 | — | |
AUVYIYPXJRILLE
|
7.8 | IC50 | 6 | — | |
DMINKKLAOYLYLD
|
7.8 | IC50 | 6 | — | |
FNVZIUZHHCMTFP
|
7.8 | IC50 | 6 | — | |
HWCUUYTXPDRXJK
|
7.8 | IC50 | 6 | — | |
MEIBAUIZWBBTLF
|
7.8 | IC50 | 6 | — | |
XCGJIFAKUZNNOR
|
7.8 | IC50 | 6 | — | |
AFHRWVCOQPVDKK
|
7.8 | IC50 | 6 | — | |
BXMBAARDPRZROY
|
7.8 | IC50 | 6 | — | |
CBZHFCPGQAUEJE
|
7.8 | IC50 | 6 | — | |
CWCGYEXUHVQRDM
|
7.8 | IC50 | 6 | — | |
GDJPLNOSDZIINK
|
7.8 | IC50 | 6 | — | |
HSYVIRSKJLZWQT
|
7.8 | IC50 | 6 | — | |
KSQVWJZRTGUBBM
|
7.8 | IC50 | 6 | — | |
LRGYTDXXVVUMFV
|
7.8 | IC50 | 6 | — | |
NMPUONCUGMQMNT
|
7.8 | IC50 | 6 | — | |
PIUIWUNTOBSJLS
|
7.8 | IC50 | 6 | — | |
RDBWLFGMGXLTQD
|
7.8 | IC50 | 7 | — | |
SNHBRHBMEDWDNF
|
7.8 | IC50 | 7 | — | |
WANTWYYPVUJSRC
|
7.8 | IC50 | 6 | — | |
XGTZKVXMDSWEOE
|
7.8 | IC50 | 6 | — | |
ANPQRNAPRJICPK
|
7.8 | IC50 | 6 | — | |
AHERSACVYXVWEK
|
7.8 | IC50 | 6 | — | |
FSQUYIAMRHDXDD
|
7.8 | IC50 | 6 | — | |
HHCGWONBKCJWOU
|
7.8 | IC50 | 6 | — | |
KVSXFSNMYXYPHW
|
7.8 | IC50 | 6 | — | |
LJGANDPIBLQDSR
|
7.8 | IC50 | 6 | — | |
OREMVQODZWZFQC
|
7.8 | IC50 | 6 | — | |
ZOVFQRDNBWHWDZ
|
7.8 | IC50 | 6 | — | |
SSPORCPQXWFZQQ
|
7.7 | IC50 | 6 | — | |
IDOAKQMETXZJBC
|
7.7 | IC50 | 6 | — | |
AGHXCKLYYIUDCG
|
7.7 | IC50 | 6 | — | |
IDOJRUZHMDUYFU
|
7.7 | IC50 | 6 | — | |
IEXICYSIZWDQOD
|
7.7 | IC50 | 6 | — | |
IVHDOVLHZVPDCB
|
7.7 | IC50 | 6 | — | |
KLZJSICNBNPIOK
|
7.7 | IC50 | 6 | — | |
KVAXCDFYKXYUNJ
|
7.7 | IC50 | 6 | — | |
QFKNPNBHMYPRLJ
|
7.7 | IC50 | 6 | — | |
VBEOQNLXYDKJOJ
|
7.7 | IC50 | 6 | — | |
ZKLZSAACDZEQLJ
|
7.7 | IC50 | 6 | — | |
BISRUWVRRYLPDL
|
7.7 | IC50 | 6 | — |