CDK12 — MultiTargetDB

Target Details

UniProt AC	`Q9NYV4`
Gene Symbol	CDK12
Protein Name	Cyclin-dependent kinase 12
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00069 (Pkinase)

Summary

Multi-target molecules 687
Clinical molecules 4
Avg pChEMBL 6.75

Top Co-occurrence Targets

CCNK 555 shared
CDK7 241 shared
CDK2 240 shared
CDK9 212 shared
CCNT1 203 shared
CCNE1 179 shared
CCNH 163 shared
MNAT1 141 shared
CDK13 82 shared
CCNA2 55 shared

Active Molecules (687)

InChIKey	pChEMBL	Type	Targets	Clinical
`COGUZYALRYMQTD`	7.6	IC50	9	—
`JNCKNVLRCXCYFJ`	7.6	IC50	2	—
`SURDWBSTQAAZRE`	7.5	IC50	2	—
`WPDAOESAFFAEIJ`	7.5	IC50	2	—
`NBSJZWFDNFWQDN`	7.5	IC50	29	—
`NISFDVKKOILICU`	7.5	IC50	8	—
`WGXYZGVVINFQEE`	7.5	IC50	2	—
`DNWIBFXHQBOSSU`	7.5	IC50	3	—
`CDSCIOFBELFZQV`	7.5	IC50	2	—
`YUETVGNBMQAYGX`	7.5	IC50	2	—
`UQKMSJFNACXHSL`	7.5	IC50	3	—
`CORSDGPCOHNHIF`	7.5	IC50	2	—
`OBLHGEMELWSIQC`	7.5	IC50	2	—
`ORKBHIKNAHONFZ`	7.5	IC50	2	—
`DGAWYBIEBJUVHR`	7.5	IC50	8	—
`VXPOWGZNPZRARA`	7.5	IC50	2	—
`DMHIYVOKOFGYMX`	7.5	IC50	2	—
`DZCKPKOLULVQCH`	7.5	IC50	2	—
`KPCQQZMELPQBCN`	7.5	IC50	3	—
`LONMOKRIWNAKRA`	7.5	IC50	2	—
`BTDWTDGMTNRFHC`	7.5	IC50	10	—
`JWJSVFGSAKPIRW`	7.5	IC50	2	—
`BFEWHEFVBQRIIR`	7.4	IC50	8	—
`QLOKXKBEVATRMM`	7.4	IC50	2	—
`YONAXDQFTJQXHL`	7.4	IC50	2	—
`NAAXETMTUYPROV`	7.4	IC50	2	—
`PFLWENDTYLYORX`	7.4	Kd	4	—
`YAOSCIXJLJNDAH`	7.4	IC50	2	—
`AFFSZQATPPOYMW`	7.4	IC50	2	—
`VSFCGHQYOCWRAL`	7.4	IC50	2	—
`AYGSWHUBBRQXAY`	7.4	IC50	2	—
`HUUCUGRZFSMNOH`	7.4	IC50	5	—
`PIMQWRZWLQKKBJ`	7.4	IC50	36	—
`VGLKGQQXJZIODI`	7.4	IC50	2	—
`XDFVYFGUZKKLGL`	7.4	IC50	2	—
`HZLPXAWTOHIUOU`	7.4	IC50	2	—
`NAHZPFSSZALDDJ`	7.4	IC50	2	—
`YKSDGHNGKNMUGI`	7.4	IC50	12	—
`BBNRKNPIGVECPW`	7.4	IC50	2	—
`GXGRNWVRDQTYLG`	7.4	IC50	2	—
`KHUOKYIRVUZOGN`	7.3	IC50	2	—
`KSUPSBDNUMSNQO`	7.3	IC50	2	—
`DJMZUWUEYULGRB`	7.3	IC50	2	—
`AKMSYPYWPJSTGX`	7.3	IC50	2	—
`UOQCGDAFQBJAIJ`	7.3	IC50	2	—
`ORQQCLLJNPKLIL`	7.3	IC50	7	—
`PFNFCPSKWUCEHW`	7.3	IC50	2	—
`GNWQPICFCPORII`	7.3	IC50	5	—
`HDRQADKZAGAURW`	7.3	IC50	2	—
`MGIDXACENIIRIH`	7.3	IC50	2	—