SPHK1 — MultiTargetDB

Target Details

UniProt AC	`Q9NYA1`
Gene Symbol	SPHK1
Protein Name	Sphingosine kinase 1
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00781 (DAGK_cat)

Summary

Multi-target molecules 60
Clinical molecules 0
Avg pChEMBL 7.34

KEGG Pathways (10)

Top Co-occurrence Targets

SPHK2 59 shared
TUBB1 1 shared
TUBB2B 1 shared
TUBB6 1 shared
TUBB8 1 shared
TUBB2A 1 shared
TUBB3 1 shared
TUBB4B 1 shared
VCP 1 shared
ALOX5 1 shared

Active Molecules (60)

InChIKey	pChEMBL	Type	Targets	Clinical
`AVMNWMSCOPMWAG`	8.7	IC50	2	—
`CJGFBPTTYOTAQL`	8.6	IC50	2	—
`SEXQYDWLUQKHJQ`	8.6	IC50	2	—
`BJIKLEJWYCWXIR`	8.5	IC50	2	—
`XIMGKTHOXDOTSY`	8.5	IC50	2	—
`NPUXORBZRBIOMQ`	8.4	IC50	2	—
`LWGVRMGYJJYXQR`	8.4	IC50	2	—
`HLECVOVYAFPDGC`	8.3	IC50	2	—
`JBIVMEZMEYVJHE`	8.3	IC50	2	—
`YFPTVJXNOYMELX`	8.3	IC50	2	—
`XVUAWKMAHFBSFJ`	8.2	IC50	2	—
`GQUZLIHRTAGSGL`	8.1	Ki	2	—
`DGHASZVHKYOGMP`	8.1	IC50	2	—
`XGVBSUDCRAOHTR`	8.1	Ki	2	—
`SSIIMVCXNBYHOC`	8.1	IC50	2	—
`IBHUFYAAAUYTER`	8.0	IC50	2	—
`IIVAMRJXZLTDKR`	8.0	IC50	2	—
`LRTJNSSXHCYTOU`	8.0	IC50	2	—
`QEOPCZCCWMDUAX`	8.0	IC50	2	—
`LQDSPOUZGCEGTF`	8.0	IC50	2	—
`ISRDJACTUWHCSE`	8.0	IC50	2	—
`SPXSEZMVRJLHQG`	7.8	IC50	2	—
`ACZJGLPLAZYYDS`	7.7	IC50	2	—
`FTJQNHOHUZLHRN`	7.7	IC50	2	—
`QRSGDELKVVKLLO`	7.7	IC50	2	—
`VPQJTFCFVWMFKD`	7.7	IC50	2	—
`WMJHXDWUTXRNRV`	7.7	IC50	2	—
`OETCYVILHFTAQU`	7.6	IC50	2	—
`GMGHOLUNDWPBND`	7.5	IC50	2	—
`GMGHOLUNDWPBND`	7.5	IC50	2	—
`WEDUOLPYCMDXQH`	7.5	IC50	2	—
`LTOXJDUJWHRAKL`	7.4	IC50	2	—
`KZMZOFCREKHNQL`	7.4	Ki	2	—
`KZMZOFCREKHNQL`	7.4	IC50	2	—
`PHNPDQFIXHTOBV`	7.4	IC50	2	—
`AONUEFSORSSSOA`	7.4	IC50	2	—
`OWBQCPZBRPKYKE`	7.2	IC50	12	—
`VRGFDZRHFXOHFN`	7.1	IC50	2	—
`ONQQJVYCDMZBNG`	6.9	Ki	2	—
`RCNOZNMHXCFQMD`	6.9	IC50	2	—
`BARORSZYYCASMF`	6.9	IC50	2	—
`PQBVBVYYHUDOMV`	6.8	IC50	2	—
`QIJHLTDUUWKGLT`	6.7	Ki	2	—
`MPXINAVXVRBCLE`	6.7	IC50	2	—
`FVDIITVBXQCLEM`	6.4	IC50	2	—
`RCNOZNMHXCFQMD`	6.4	IC50	2	—
`AVZCFCKDKZNMPU`	6.4	IC50	2	—
`ZFGXZJKLOFCECI`	6.3	IC50	5	—
`DEROCFAOMRTOOK`	6.2	Ki	2	—
`ULYXSNVEHKBRQG`	6.2	IC50	2	—