Target Details
| UniProt AC | Q9NTG7 |
|---|---|
| Gene Symbol | SIRT3 |
| Protein Name | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF02146 (SIR2) |
Summary
- Multi-target molecules 64
- Clinical molecules 0
- Avg pChEMBL 6.85
KEGG Pathways (3)
Active Molecules (64)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
XZEVSGANERUOOE
|
8.5 | IC50 | 3 | — | |
IXDTWYVAYLILOL
|
8.4 | IC50 | 3 | — | |
JSCRCECGNHPGDY
|
8.3 | IC50 | 3 | — | |
KZYJYQLNHZCLDV
|
8.3 | IC50 | 3 | — | |
BKOWIHMCGFRARN
|
8.1 | IC50 | 3 | — | |
CLHJWTGEHRKCOS
|
8.1 | IC50 | 3 | — | |
NOIHKZDGMKIHMS
|
7.9 | IC50 | 3 | — | |
PHJKODPPONELIT
|
7.6 | IC50 | 3 | — | |
VDDQOGYORIZJNZ
|
7.6 | IC50 | 3 | — | |
QQSPATQSWSHBGK
|
7.5 | IC50 | 3 | — | |
CQMOSWGPJHVHLC
|
7.5 | IC50 | 3 | — | |
TUPOUUWFQWSCOF
|
7.5 | IC50 | 3 | — | |
NSPKBHVNVJWICU
|
7.5 | IC50 | 3 | — | |
TZDSTEUXHBSJJN
|
7.4 | IC50 | 3 | — | |
AZWUHEDTRIRBNH
|
7.4 | IC50 | 3 | — | |
DCTRQERVJUJWET
|
7.4 | IC50 | 3 | — | |
JQMNHTYSZNHCJL
|
7.3 | IC50 | 3 | — | |
KHHINHQHUHGNAF
|
7.2 | IC50 | 3 | — | |
ANBJLSODZNSLHK
|
7.2 | IC50 | 3 | — | |
UQYCPGDIEUPDPU
|
7.2 | IC50 | 3 | — | |
GMILTSIKPMSSBB
|
7.2 | IC50 | 3 | — | |
KTHAWFPSAOFRDZ
|
7.2 | IC50 | 3 | — | |
HEMQTRCOHWZDFV
|
7.1 | IC50 | 4 | — | |
OWKCFFYUTGURHW
|
7.1 | IC50 | 3 | — | |
VFTCCJSLGAXIGU
|
7.0 | IC50 | 3 | — | |
IMFVZYLIKDQVRH
|
7.0 | IC50 | 3 | — | |
DOWRENKIYTXIHE
|
7.0 | IC50 | 3 | — | |
PADFWVDPPOPSCS
|
7.0 | IC50 | 3 | — | |
DGTXIKMZQXJEGK
|
6.9 | IC50 | 3 | — | |
YXALICSPLRPVAX
|
6.9 | Ki | 2 | — | |
NVZUKEJLRYCMHJ
|
6.8 | IC50 | 3 | — | |
GEYPZCRKECPUOD
|
6.8 | IC50 | 3 | — | |
UZQHOVMGMUVGDB
|
6.8 | IC50 | 3 | — | |
QSPDOXSSJZUJOC
|
6.7 | IC50 | 3 | — | |
PKQZWUNVYCCIES
|
6.6 | IC50 | 3 | — | |
IAZIQOBNUOFMFE
|
6.5 | IC50 | 3 | — | |
YJIAXMSFKWGHSX
|
6.5 | IC50 | 2 | — | |
KVSDGRKQUMZINU
|
6.5 | IC50 | 2 | — | |
QXTKWWOUIXSBEW
|
6.4 | IC50 | 3 | — | |
LYVMXHPJNVMUKZ
|
6.3 | IC50 | 2 | — | |
IEHBGAHJQRMSCS
|
6.3 | IC50 | 3 | — | |
GVDVRWSREIPDDL
|
6.3 | IC50 | 3 | — | |
FPGVQKQGQCIGCO
|
6.3 | IC50 | 3 | — | |
XYMIRODCWAPIPL
|
6.3 | IC50 | 2 | — | |
CWPWATULNKVZGA
|
6.3 | IC50 | 2 | — | |
XQSWNESGOFOJLG
|
6.3 | IC50 | 2 | — | |
JRCPIIDXDIJIHX
|
6.3 | IC50 | 2 | — | |
GMZDEAOPWMNJSR
|
6.2 | IC50 | 2 | — | |
PFDJAZISMIJOOW
|
6.2 | IC50 | 2 | — | |
LPBVBHBFWUMHMQ
|
6.2 | IC50 | 3 | — |