IARS2 — MultiTargetDB

Target Details

UniProt AC	`Q9NSE4`
Gene Symbol	IARS2
Protein Name	Isoleucine--tRNA ligase, mitochondrial
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF08264 (Anticodon_1) PF00133 (tRNA-synt_1) PF06827 (zf-FPG_IleRS)

Summary

Multi-target molecules 2
Clinical molecules 0
Avg pChEMBL 7.04

KEGG Pathways (1)

Aminoacyl-tRNA biosynthesis

Associated Diseases (1)

CAGSSS syndrome

Top Co-occurrence Targets

MAP2K1 2 shared
SEC23IP 1 shared
MAP3K4 1 shared
NDUFB9 1 shared
TEX264 1 shared
DYNC1LI1 1 shared
ARFGEF1 1 shared
MTCH2 1 shared
CLIC4 1 shared
PSAT1 1 shared

Active Molecules (2)

InChIKey	pChEMBL	Type	Targets	Clinical
`VIUAUNHCRHHYNE`	8.0	Kd	3	—
`MWKSRKSEWLRPBL`	6.1	Kd	1075	—