Target Details
| UniProt AC | Q9NQB0 |
|---|---|
| Gene Symbol | TCF7L2 |
| Protein Name | Transcription factor 7-like 2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF08347 (CTNNB1_binding) PF00505 (HMG_box) |
Summary
- Multi-target molecules 154
- Clinical molecules 0
- Avg pChEMBL 6.29
KEGG Pathways (21)
- Acute myeloid leukemia
- Adherens junction
- Alcoholic liver disease
- Arrhythmogenic right ventricular cardiomyopathy
- Basal cell carcinoma
- Breast cancer
- Cadherin signaling
- Colorectal cancer
- Cushing syndrome
- Endometrial cancer
- Gastric cancer
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human papillomavirus infection
- Kaposi sarcoma-associated herpesvirus infection
- Melanogenesis
- Pathways in cancer
- Prostate cancer
- Salmonella infection
- Thyroid cancer
- Wnt signaling pathway
Associated Diseases (1)
Active Molecules (154)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
FDQIPUBUNUJHCQ
|
6.0 | IC50 | 2 | — | |
BCIHVYADZVHSSY
|
6.0 | IC50 | 2 | — | |
HNYYTPIJUOUJEA
|
6.0 | IC50 | 2 | — | |
PQPJKBSPXRPUKP
|
6.0 | IC50 | 2 | — |