Target Details
| UniProt AC | Q9HC29 |
|---|---|
| Gene Symbol | NOD2 |
| Protein Name | Nucleotide-binding oligomerization domain-containing protein 2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00619 (CARD) PF13516 (LRR_6) PF05729 (NACHT) PF17776 (NLRC4_HD2) PF17779 (WHD_NOD2) |
Summary
- Multi-target molecules 60
- Clinical molecules 1
- Avg pChEMBL 6.87
KEGG Pathways (4)
Associated Diseases (3)
Active Molecules (60)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GUGWAPHGUQVWRA
|
9.0 | IC50 | 3 | — | |
YBDMDASOVBUGSC
|
8.5 | IC50 | 3 | — | |
ALEALKZBRLEOJZ
|
8.4 | IC50 | 3 | — | |
CWORZSMRYNSMCN
|
8.3 | IC50 | 3 | — | |
QXZQWTRSWYLAFO
|
8.3 | IC50 | 3 | — | |
UHDOJINBFLDQJM
|
8.1 | IC50 | 2 | — | |
KWZMLARYZJWIGD
|
8.1 | IC50 | 3 | — | |
WUEJFDOJIBRVBJ
|
7.9 | IC50 | 3 | — | |
XGUIEYMNFRMLPV
|
7.8 | IC50 | 6 | — | |
CUAUTGRQMYJPFC
|
7.8 | IC50 | 5 | — | |
QXIDSSPGGSFJDS
|
7.8 | IC50 | 3 | — | |
CNHAKFYAPGFFRH
|
7.7 | IC50 | 2 | — | |
GHIRKOYLRMQNAF
|
7.7 | IC50 | 3 | — | |
AMLGBGSXVKQKOZ
|
7.6 | IC50 | 3 | — | |
LAMPPZAYRXOJOM
|
7.5 | IC50 | 3 | — | |
DDYGZGMTWMFEHB
|
7.4 | IC50 | 2 | — | |
IFPPYSWJNWHOLQ
|
7.4 | IC50 | 52 | Yes | |
CSEOMSQIOBWXNZ
|
7.3 | IC50 | 3 | — | |
GTJCBPZCSZZPQO
|
7.3 | IC50 | 3 | — | |
JBTJGPURAPMJSS
|
7.3 | IC50 | 3 | — | |
VNJSERLEIJDSJV
|
7.0 | IC50 | 2 | — | |
CWQBNTNIMPDAEK
|
7.0 | IC50 | 2 | — | |
AGBKRFXLWIHJQH
|
6.9 | IC50 | 3 | — | |
XAVIPIHNPPAYAJ
|
6.9 | IC50 | 3 | — | |
JTWDQFJHOKLOHG
|
6.9 | IC50 | 3 | — | |
LATMRUSMLRSPOU
|
6.8 | IC50 | 2 | — | |
ZOLPTXOZGBDIDY
|
6.7 | IC50 | 2 | — | |
VKZQLCDUHSNDRE
|
6.6 | IC50 | 2 | — | |
WAOTXMYGOSUFGX
|
6.6 | IC50 | 3 | — | |
WWBBFDGOQJQXFK
|
6.6 | IC50 | 3 | — | |
AOFHPWKDAJCJHE
|
6.6 | IC50 | 2 | — | |
RRNARHMPEAENRG
|
6.5 | IC50 | 2 | — | |
JCEWXHIMEBYYPB
|
6.5 | IC50 | 2 | — | |
WTNLXMJMLHJDKF
|
6.4 | IC50 | 3 | — | |
PFNLTXPEWXUGPM
|
6.4 | IC50 | 3 | — | |
YDOATJUIIFWTKQ
|
6.4 | IC50 | 2 | — | |
JMJHOMFUECZGAD
|
6.4 | IC50 | 2 | — | |
WQSZXQCNJGOWQU
|
6.4 | IC50 | 2 | — | |
OMLZCXJVYHKTKX
|
6.3 | IC50 | 2 | — | |
STJGPPVIWXNZDP
|
6.3 | IC50 | 2 | — | |
RXINECZBKGCLEK
|
6.3 | IC50 | 2 | — | |
MCKKWYKONXTPFI
|
6.3 | IC50 | 3 | — | |
NMRXGLAXNGJRIR
|
6.3 | IC50 | 2 | — | |
RYZBUWPYJXKFMR
|
6.2 | IC50 | 2 | — | |
BYIUTBBPZFVDJL
|
6.2 | IC50 | 4 | — | |
DKEHSDCAAWFLHB
|
6.2 | IC50 | 3 | — | |
UIIXJLLQKFFGKU
|
6.2 | IC50 | 3 | — | |
HGOZASPSWPDZQN
|
6.2 | IC50 | 2 | — | |
SBTAGVYSJMZSQE
|
6.1 | IC50 | 2 | — | |
OUPVCASXISVAPH
|
6.1 | IC50 | 3 | — |