Target Details
| UniProt AC | Q9H4B4 |
|---|---|
| Gene Symbol | PLK3 |
| Protein Name | Serine/threonine-protein kinase PLK3 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) PF00659 (POLO_box) |
Summary
- Multi-target molecules 203
- Clinical molecules 24
- Avg pChEMBL 6.88
KEGG Pathways (3)
Active Molecules (203)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
NDIUYMHNCUTVGE
|
8.7 | Ki | 25 | — | |
XSTRJMHOLBBWNN
|
8.3 | IC50 | 4 | — | |
ABXJJVJJEAFTLI
|
8.3 | IC50 | 4 | — | |
CXJOVIBONXRCNI
|
8.3 | IC50 | 2 | — | |
WPYKLBCLPYHTFI
|
8.3 | IC50 | 2 | — | |
XQVVPGYIWAGRNI
|
8.3 | Ki | 19 | — | |
NHHQJBCNYHBUSI
|
8.3 | Kd | 220 | — | |
OVNJVYZXVSMONK
|
8.2 | IC50 | 3 | — | |
OXPLZKSKLWBEIM
|
8.2 | IC50 | 8 | Yes | |
PWEVQXOSGNAHIQ
|
8.2 | IC50 | 2 | — | |
UHCHLTQBLNUYRT
|
8.2 | IC50 | 2 | — | |
XANXBCMPWPUNSZ
|
8.2 | IC50 | 3 | — | |
YMIJUBCSOKSFRU
|
8.2 | Ki | 87 | — | |
MOIBHLHUAXJLCW
|
8.2 | IC50 | 5 | — | |
NYYQMOVTQNHDLM
|
8.2 | IC50 | 4 | — | |
CQQFCBITQKNHPX
|
8.1 | IC50 | 4 | — | |
DNFIELFWKQLTEZ
|
8.1 | IC50 | 2 | — | |
JSKUWFIZUALZLX
|
8.1 | IC50 | 33 | — | |
KFJDFQDPJGBOJE
|
8.1 | IC50 | 4 | — | |
WRWFZZDBIJLBIJ
|
8.1 | IC50 | 2 | — | |
RTDGHNXXZKSIDE
|
8.0 | IC50 | 3 | — | |
QXAKKDDDYAESLJ
|
8.0 | IC50 | 6 | Yes | |
XQVVPGYIWAGRNI
|
8.0 | IC50 | 34 | — | |
QUFVOKRHVJFMNM
|
7.9 | IC50 | 8 | Yes | |
FLEAYYMORDPWAJ
|
7.9 | Ki | 90 | — | |
QPTZMGCTRHKKJD
|
7.9 | Ki | 3 | — | |
RKKIDHHGKNGTQI
|
7.9 | Ki | 28 | — | |
AOYIAMTYZLMCGR
|
7.9 | IC50 | 2 | — | |
DPROZSHCTFNYSW
|
7.9 | IC50 | 6 | Yes | |
XEMJTISGDXHELX
|
7.9 | IC50 | 8 | Yes | |
UTHWBIPHRYUJSU
|
7.8 | IC50 | 11 | Yes | |
CKVWQORGCCEYHS
|
7.8 | Ki | 50 | — | |
CVPAFJFHWHMNPA
|
7.8 | IC50 | 2 | — | |
MIKAKZKNMYZLDX
|
7.8 | Ki | 42 | — | |
OQIVVQXVRCAEIO
|
7.8 | IC50 | 2 | — | |
UNZVQIJLQQYQLN
|
7.8 | IC50 | 6 | — | |
IAIOBCSUUBVREO
|
7.7 | IC50 | 8 | Yes | |
OCYISXRMEJNANP
|
7.7 | IC50 | 3 | — | |
OSCRFGZIFNWYIZ
|
7.7 | IC50 | 3 | — | |
DAAGOCSHXCDWDY
|
7.6 | IC50 | 3 | — | |
GCBJDOWIQHMCMR
|
7.6 | Ki | 84 | — | |
IBAYIPZJRQHHLX
|
7.6 | IC50 | 2 | — | |
FGUYNCHKIOFPMS
|
7.5 | IC50 | 2 | — | |
JYYQJHRWOKIHGC
|
7.5 | IC50 | 3 | — | |
AAVMTXYKUJWQBU
|
7.5 | IC50 | 8 | Yes | |
GCFCQBCBKXQUCD
|
7.5 | IC50 | 3 | — | |
JAMDNXUAYUHJLJ
|
7.5 | Ki | 40 | — | |
YWNUJKWNTHEOIR
|
7.5 | IC50 | 2 | — | |
OYDGHJTZNAFKAQ
|
7.4 | IC50 | 6 | Yes | |
PRMNYSLMFFRETJ
|
7.4 | IC50 | 3 | — |