Target Details
UniProt ACQ9BY41
Gene SymbolHDAC8
Protein NameHistone deacetylase 8
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00850 (Hist_deacetyl)
UniProt
Summary
  • Multi-target molecules 2,947
  • Clinical molecules 486
  • Avg pChEMBL 6.92
KEGG Pathways (4)
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (2,947)
InChIKey pChEMBL Type Targets Clinical
YOCXDMADYDMZTB 7.2 IC50 5 —
YYSCXBPFYMVUDP 7.2 IC50 7 —
DGBHRORIOASTEY 7.2 IC50 11 —
GAZWXVIVAKKMPK 7.2 IC50 6 —
GOXHRQVZGNSLMQ 7.2 IC50 11 —
ICFCPTJGLMKNHK 7.2 IC50 12 Yes
IPASVCJCQJHPFT 7.2 IC50 3 —
JGLOTFCAJROWHW 7.2 IC50 12 Yes
KOSVTVKMCBIXDN 7.2 IC50 11 —
LIZWRHXVIWNMIS 7.2 IC50 12 Yes
MLXMFZJHYAXNKI 7.2 IC50 11 —
PDJYPYKSKXLCDW 7.2 IC50 11 —
QQUIELKEKZKGMG 7.2 IC50 11 —
ZAYLUWNMUDXEOV 7.2 IC50 11 —
AGWREEWCXLWOFK 7.2 IC50 11 —
CHRCTGGFVRLKGH 7.2 IC50 11 —
FBOCYJOSWGKQAM 7.2 IC50 11 —
HLNCULXJFNWYKC 7.2 IC50 14 Yes
ILCBWDQDWOLKIQ 7.2 IC50 7 —
LZODJSNRNSCPJV 7.2 IC50 7 —
MRQFZMGSPGRHGO 7.2 IC50 11 —
NJPJWEDRLRTSLU 7.2 IC50 11 Yes
VCQGMJZYDYIFCF 7.2 IC50 4 —
XGYQZARMEBVCNN 7.2 IC50 3 —
XLQQMWWWMUPVLL 7.2 IC50 11 —
CTNAJMVWCJOHQE 7.2 IC50 3 —
LXWYRQJNEXQFOY 7.2 IC50 4 Yes
ONGPNIKNCOQYLB 7.2 IC50 4 —
QSRHSFQEQDXNSP 7.2 IC50 4 —
SLARRDVFWGBXGX 7.2 IC50 4 Yes
UYZBNNODRNHVBB 7.2 IC50 12 Yes
VINFAVNHTFQZFB 7.2 IC50 4 Yes
WVZBQUZVOYIGLK 7.2 IC50 3 —
XUADSMRILXQYKS 7.2 IC50 4 Yes
XYWOQDSCIWZFQS 7.2 IC50 4 Yes
ZDHGLVMTPWCPNI 7.2 IC50 4 Yes
ZLUZDKXBTNQWOL 7.2 IC50 12 Yes
AHHNXKYEHPZBNR 7.2 IC50 3 —
AIEQMVYBDDVIPP 7.2 IC50 3 —
APFBRKWRVAGAHZ 7.2 IC50 11 —
FDURBWFXDKGGLQ 7.2 Ki 12 Yes
GPGGCNQZIWRUGW 7.2 IC50 11 —
IMRRVABDEDKYSP 7.2 IC50 4 —
PRIUJKXYEBCDBF 7.2 IC50 11 —
PVGQSDDJHXMAHC 7.2 IC50 4 —
SUIWTHQZBYYCGP 7.2 IC50 3 —
SZVAVGPGKWOHGK 7.2 IC50 11 —
ZBKIYZUDBOQUME 7.2 IC50 4 —
ZCJNQRRQDXSGEO 7.2 IC50 2 —
ABKYAMSVHWBFGO 7.2 IC50 3 —
2D structure