Target Details
| UniProt AC | Q9BUB5 |
|---|---|
| Gene Symbol | MKNK1 |
| Protein Name | MAP kinase-interacting serine/threonine-protein kinase 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) |
Summary
- Multi-target molecules 445
- Clinical molecules 13
- Avg pChEMBL 7.24
KEGG Pathways (3)
Active Molecules (445)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GBZIOQYCTAFXKL
|
10.1 | IC50 | 2 | — | |
STQNTZGKYOJTGA
|
9.8 | IC50 | 2 | — | |
RLDAVKBTPHGEED
|
9.4 | IC50 | 2 | — | |
JEOHNIZYSBQLBI
|
9.1 | IC50 | 2 | — | |
XCYFTLJVXBVKHG
|
9.1 | IC50 | 2 | — | |
LGDROMVQTALVNT
|
9.1 | IC50 | 3 | — | |
FWTKVRZMQJINSD
|
9.0 | IC50 | 5 | — | |
NPZBGSCEEAHWNK
|
9.0 | IC50 | 2 | — | |
CDWDPWNPTCKJNW
|
9.0 | IC50 | 2 | — | |
HFTAYZLGTCEXAY
|
9.0 | IC50 | 2 | — | |
LEAJNJJPWHYFJT
|
8.9 | IC50 | 2 | — | |
DHFSWODVDVUGGC
|
8.8 | IC50 | 3 | — | |
RZKFMYXHNVBJJV
|
8.8 | IC50 | 2 | — | |
LRFZYWGMOLOLPZ
|
8.7 | IC50 | 2 | — | |
VQBHHVIUAXNAOC
|
8.7 | IC50 | 3 | — | |
MIVZVCNGBMCBAA
|
8.7 | IC50 | 3 | — | |
JONIGSIXPCHLPF
|
8.7 | IC50 | 3 | — | |
RBEFDXXUUNMTSK
|
8.7 | IC50 | 2 | — | |
AJGPWESAFONVCG
|
8.7 | IC50 | 3 | — | |
RKNGTCDEHZFRSK
|
8.6 | IC50 | 2 | — | |
DCUJQHLLVMQMID
|
8.6 | IC50 | 2 | — | |
RWDCJKPJKMBFCI
|
8.6 | IC50 | 2 | — | |
CYFVVHXJLAKHJY
|
8.6 | IC50 | 3 | — | |
QSNAMJCLIIQNPP
|
8.6 | IC50 | 2 | — | |
CMPBIALPWFHSMB
|
8.6 | IC50 | 2 | — | |
HKTBYUWLRDZAJK
|
8.6 | IC50 | 5 | — | |
MECRYAMPAYEHHW
|
8.6 | IC50 | 2 | — | |
WCADNSJQHAGKBX
|
8.5 | IC50 | 3 | — | |
FBTRDJIPJVBTHV
|
8.5 | IC50 | 6 | — | |
WCADNSJQHAGKBX
|
8.5 | IC50 | 3 | — | |
NQKUBPWGXDRNCR
|
8.5 | IC50 | 3 | — | |
XZUIPTFXIKGMGA
|
8.5 | IC50 | 3 | — | |
GXUYZVYTXZYDQM
|
8.5 | IC50 | 3 | — | |
ZRIDICSQDPQVEH
|
8.4 | IC50 | 3 | — | |
LXNUFRAUJVQQOV
|
8.4 | IC50 | 3 | — | |
POSZZZFFLNLQCL
|
8.4 | IC50 | 3 | — | |
BFUCQUQBTJOBTA
|
8.4 | IC50 | 3 | — | |
CIWGILRASQNZHL
|
8.4 | IC50 | 2 | — | |
OEVBYHNIUPOXDX
|
8.4 | IC50 | 2 | — | |
VDWADUHIPOMAQX
|
8.4 | IC50 | 3 | — | |
YWGKAMKQNIIHHH
|
8.4 | IC50 | 2 | — | |
ZFLMJVWYYRFNEP
|
8.4 | IC50 | 2 | — | |
IPJHWPFFKVRFPR
|
8.4 | IC50 | 2 | — | |
HDKZJMGFRSXWSJ
|
8.4 | IC50 | 3 | — | |
BTVOPBCDBRHMPF
|
8.3 | IC50 | 3 | — | |
KVMZDBZVXUKZOT
|
8.3 | IC50 | 2 | — | |
BBQVZHIHIVJRIC
|
8.3 | IC50 | 2 | — | |
XRIMGCCVXQKXAF
|
8.3 | IC50 | 2 | — | |
JMOODDNVNBVCOJ
|
8.3 | IC50 | 3 | — | |
MWXOTOIFWCYXRK
|
8.3 | IC50 | 3 | — |