Target Details
| UniProt AC | Q99814 |
|---|---|
| Gene Symbol | EPAS1 |
| Protein Name | Endothelial PAS domain-containing protein 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF23171 (bHLH_HIF1A) PF11413 (HIF-1) PF08778 (HIF-1a_CTAD) PF00989 (PAS) PF14598 (PAS_11) |
Summary
- Multi-target molecules 107
- Clinical molecules 0
- Avg pChEMBL 6.88
KEGG Pathways (3)
Associated Diseases (2)
Active Molecules (107)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ZCYJIVITFYSOPQ
|
9.3 | IC50 | 2 | — | |
TWWJWKGWDGOUJI
|
9.0 | IC50 | 2 | — | |
WGKHIIOJTRYMFF
|
9.0 | IC50 | 2 | — | |
TVPBLVZJMMMTJV
|
8.6 | IC50 | 2 | — | |
BHSIFEWQADUTCG
|
8.5 | IC50 | 2 | — | |
GSWZMFDCPMPHDL
|
8.5 | IC50 | 2 | — | |
VZXIZTQHELIFBK
|
8.5 | IC50 | 2 | — | |
XVUZWQZVGNYBAU
|
8.5 | IC50 | 2 | — | |
AQRLWUHZRVSEBX
|
8.2 | IC50 | 2 | — | |
MUTIAFGLMQDVIR
|
8.1 | IC50 | 2 | — | |
QGRLEGRRTOCLPO
|
8.1 | IC50 | 2 | — | |
RSHYSOGXGSUUIJ
|
8.1 | IC50 | 2 | — | |
ONBSHRSJOPSEGS
|
7.9 | IC50 | 2 | — | |
QRLXTLZFDOVBMT
|
7.9 | IC50 | 2 | — | |
DUTYSEGHLWMISZ
|
7.9 | IC50 | 2 | — | |
XNODZYPOIPVPRF
|
7.9 | IC50 | 2 | — | |
XVUZWQZVGNYBAU
|
7.9 | IC50 | 2 | — | |
CMWPPRIRZXEXDM
|
7.8 | IC50 | 2 | — | |
HZDKYXAZAPXCKQ
|
7.8 | IC50 | 2 | — | |
UCGGKWXRURDYEP
|
7.7 | IC50 | 2 | — | |
YPMOWWPVPPPBET
|
7.7 | IC50 | 2 | — | |
BAECAPJWZMSHMJ
|
7.5 | IC50 | 2 | — | |
WQSGIPAMJXWYGZ
|
7.5 | IC50 | 2 | — | |
AXIGJAOOOZKTOP
|
7.5 | IC50 | 2 | — | |
BAECAPJWZMSHMJ
|
7.5 | IC50 | 2 | — | |
YPHMISFOHDHNIV
|
7.4 | IC50 | 6 | — | |
KKXLHPYVIGADHN
|
7.3 | IC50 | 2 | — | |
UWHUYKGCGHNLEP
|
7.3 | IC50 | 2 | — | |
JDUPIUFRVRIPBS
|
7.3 | IC50 | 2 | — | |
NQHCZTHBPKJWBK
|
7.3 | IC50 | 2 | — | |
FWKQVEJQEQRFGU
|
7.3 | IC50 | 2 | — | |
ODNKSLDGFCIXQD
|
7.3 | IC50 | 2 | — | |
LEZNRZJCVJRZHO
|
7.2 | IC50 | 2 | — | |
ITVZPGUBVVWDLH
|
7.2 | IC50 | 2 | — | |
PHQHXQAFRAVKSP
|
7.1 | IC50 | 2 | — | |
AUVVAXYIELKVAI
|
7.0 | IC50 | 10 | — | |
CDQUJZKBRAFWNG
|
7.0 | IC50 | 2 | — | |
ZSQSPMPLTBBXJV
|
7.0 | IC50 | 2 | — | |
SSIWQCYLGHKCQZ
|
6.9 | IC50 | 2 | — | |
WLYHQGRWWJUGPS
|
6.9 | IC50 | 2 | — | |
GUJWSWZIXSWLTL
|
6.9 | IC50 | 2 | — | |
ASNDCRBLPOKXJR
|
6.8 | IC50 | 2 | — | |
KVBRHUQRAWRYAI
|
6.8 | IC50 | 2 | — | |
FUUWQJVNALIXDT
|
6.8 | Kd | 2 | — | |
FXUKXNSGAXJPHR
|
6.8 | Kd | 2 | — | |
PVQSVWLZGINSSA
|
6.8 | Kd | 2 | — | |
IIFHKWNCTVOSKL
|
6.7 | IC50 | 2 | — | |
KYTFUEKZQZLJCC
|
6.7 | IC50 | 2 | — | |
XZLDMUNIMNCFCN
|
6.7 | IC50 | 2 | — | |
LLQXGXPLKBHEAI
|
6.7 | IC50 | 2 | — |