Target Details
UniProt ACQ99759
Gene SymbolMAP3K3
Protein NameMitogen-activated protein kinase kinase kinase 3
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00564 (PB1) PF00069 (Pkinase)
Summary
  • Multi-target molecules 26
  • Clinical molecules 12
  • Avg pChEMBL 6.82
Associated Diseases (1)
Top Co-occurrence Targets
Active Molecules (26)
InChIKey pChEMBL Type Targets Clinical
UIARLYUEJFELEN 8.2 Kd 289 Yes
HKSZLNNOFSGOKW 8.0 IC50 408
MWKSRKSEWLRPBL 7.6 Kd 1075
YRDHKIFCGOZTGD 7.5 IC50 21
XZXHXSATPCNXJR 7.5 Kd 165 Yes
UBPYILGKFZZVDX 7.3 Kd 130 Yes
KTEIFNKAUNYNJU 7.0 Kd 114
YYLKKYCXAOBSRM 6.9 Kd 191
JWNPDZNEKVCWMY 6.9 Kd 57 Yes
HFNKQEVNSGCOJV 6.8 Kd 65
NHHQJBCNYHBUSI 6.8 Kd 220
ZCBUQCWBWNUWSU 6.8 Kd 59
BMGQWWVMWDBQGC 6.7 Kd 147 Yes
GUBJNPWVIUFSTR 6.7 Kd 103
WINHZLLDWRZWRT 6.7 Kd 201 Yes
RYYNGWLOYLRZLK 6.6 Kd 45
ZBNZXTGUTAYRHI 6.5 Kd 102 Yes
CTNPALGJUAXMMC 6.5 Kd 151
QQWUGDVOUVUTOY 6.5 Kd 231 Yes
LOLPPWBBNUVNQZ 6.5 Kd 97 Yes
VAARYSWULJUGST 6.4 Kd 119 Yes
DKZYXHCYPUVGAF 6.4 Kd 112
CSGQVNMSRKWUSH 6.3 Kd 21
MFAQYJIYDMLAIM 6.2 Kd 130 Yes
YLCFOHVAOBLAIK 6.1 IC50 14
KGPGFQWBCSZGEL 6.1 Kd 59 Yes
2D structure