Target Details
| UniProt AC | Q96BI3 |
|---|---|
| Gene Symbol | APH1A |
| Protein Name | Gamma-secretase subunit APH-1A |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF06105 (Aph-1) |
Summary
- Multi-target molecules 1,927
- Clinical molecules 1
- Avg pChEMBL 7.37
KEGG Pathways (3)
Active Molecules (1,927)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
VBMYTMZKJLTLPO
|
8.1 | IC50 | 6 | — | |
YMPVSJOLUDGEGQ
|
8.1 | IC50 | 6 | — | |
ZOYWVBKIJSBNDB
|
8.1 | IC50 | 6 | — | |
FGJUUCNIIOCRBC
|
8.1 | IC50 | 6 | — | |
FVMSLFYQMWOIFN
|
8.1 | IC50 | 6 | — | |
GQLYTFBOIYIDOU
|
8.1 | IC50 | 7 | — | |
OLLCSNPRGPMBHT
|
8.1 | IC50 | 7 | — | |
HICUGCLVDIWIIB
|
8.1 | IC50 | 6 | — | |
XLPQYPXPTMEQNC
|
8.1 | IC50 | 6 | — | |
AWDGOLBDZGNTFZ
|
8.1 | IC50 | 6 | — | |
NAUFYJYYOZPDMK
|
8.1 | IC50 | 6 | — | |
VOQKFRKBIAKGJR
|
8.1 | IC50 | 6 | — | |
VVHUWYGKZMJRGQ
|
8.1 | IC50 | 6 | — | |
FNNINZNYEROZDW
|
8.1 | IC50 | 6 | — | |
HQYSCKUOKYGELX
|
8.1 | IC50 | 6 | — | |
JTVCWQUNPMKMER
|
8.1 | IC50 | 7 | — | |
ADNVRQBIELTLTL
|
8.1 | IC50 | 6 | — | |
GGTOKLPPMHMCOK
|
8.1 | IC50 | 6 | — | |
GMBOLUSXSNCWAM
|
8.1 | IC50 | 6 | — | |
HBFMUUUSKSRLLI
|
8.1 | IC50 | 6 | — | |
MUDLWRHYTYCFBR
|
8.1 | IC50 | 6 | — | |
NYCAJGBSVDYKKD
|
8.1 | IC50 | 6 | — | |
ROILOPRQCLXNJN
|
8.1 | IC50 | 6 | — | |
IZAOBRWCUGOKNH
|
8.0 | IC50 | 6 | — | |
BHPKZTGYPPFGGC
|
8.0 | IC50 | 6 | — | |
DBBDPKUPNWYZPS
|
8.0 | IC50 | 6 | — | |
ZLFSNVWAHBDKKJ
|
8.0 | IC50 | 6 | — | |
BABVQHAUMWGULB
|
8.0 | IC50 | 6 | — | |
AIIXJIZRCORSOE
|
8.0 | IC50 | 6 | — | |
BTCOCIJZIJLOOZ
|
8.0 | IC50 | 6 | — | |
CRTQUEFRKWZDSB
|
8.0 | IC50 | 6 | — | |
GUPYEUJDVZGHHN
|
8.0 | IC50 | 6 | — | |
HWZSDECUKARGIQ
|
8.0 | IC50 | 6 | — | |
HXEHCCYOTHDPPI
|
8.0 | IC50 | 6 | — | |
IDSNSUWRAQDGGL
|
8.0 | IC50 | 6 | — | |
IPNFBSNZTPJANP
|
8.0 | IC50 | 6 | — | |
MIQMEJLKMKROBE
|
8.0 | IC50 | 6 | — | |
NFNBEZTVDDCWJB
|
8.0 | IC50 | 6 | — | |
OHQWUKZYZSMZAC
|
8.0 | IC50 | 7 | — | |
OTICQHIWXNAJOV
|
8.0 | IC50 | 6 | — | |
RPMAGSXCVXNPGV
|
8.0 | IC50 | 6 | — | |
TYVIBVCYDWBTNJ
|
8.0 | IC50 | 6 | — | |
UBFWMYVCIZHIEY
|
8.0 | IC50 | 6 | — | |
UNTHRMMZVRJKBA
|
8.0 | IC50 | 7 | — | |
VNPRUYSKXQAITL
|
8.0 | IC50 | 6 | — | |
WDEKUGNKKOGFOA
|
8.0 | IC50 | 6 | — | |
XSWAREIQLKWHDM
|
8.0 | IC50 | 6 | — | |
MJLRPASHEJEXBJ
|
8.0 | IC50 | 7 | — | |
DHKAZVAQQFUSEE
|
8.0 | IC50 | 6 | — | |
LNWFRQFAJKYOTN
|
8.0 | IC50 | 6 | — |