Target Details
UniProt ACQ96BI3
Gene SymbolAPH1A
Protein NameGamma-secretase subunit APH-1A
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF06105 (Aph-1)
UniProt
Summary
  • Multi-target molecules 1,927
  • Clinical molecules 1
  • Avg pChEMBL 7.37
KEGG Pathways (3)
Top Co-occurrence Targets
Active Molecules (1,927)
InChIKey pChEMBL Type Targets Clinical
DHQUNLBGYOSXPK 7.3 IC50 6 —
GGCYEJXAWFPQOL 7.3 IC50 6 —
GLGDBYLXQPBSPN 7.3 IC50 6 —
GRMCXFXAFGCXTM 7.3 IC50 7 —
IFPBWXNUXWIDSN 7.3 IC50 6 —
JTZXPIQSOSMKQQ 7.3 IC50 6 —
MNURMQZMJMYZFQ 7.3 IC50 6 —
MZLHBHJWAVLXBF 7.3 IC50 6 —
OTTOBVPVVCGHMA 7.3 IC50 6 —
QZITUMLLZQLARP 7.3 IC50 6 —
VJEQPNRMMOUJHW 7.3 IC50 6 —
CVSZEQAPNUBXIH 7.3 IC50 6 —
GZTWUFUPZYFPHL 7.3 IC50 6 —
KASYJQGZUCQXQO 7.3 IC50 6 —
KEUUFBMIEKZMNE 7.3 IC50 6 —
NHQULVGPUDQTSC 7.3 IC50 6 —
PUBWZOHDDYWHMC 7.3 IC50 6 —
QYUHVBYDLCRTAW 7.3 IC50 6 —
TZQLYCNVGXOARB 7.3 IC50 6 —
UXDBRWRDVOSHLO 7.3 IC50 6 —
WHTOUULQSYTABS 7.3 IC50 6 —
XLOOWDYSOUYPIQ 7.3 IC50 6 —
YPEBFRLSFJTTLH 7.3 IC50 6 —
YSSDLRQAOJLLFT 7.3 IC50 7 —
VFLOCXPTWZLDFY 7.3 IC50 7 —
BZLFIPHWLWRNRG 7.3 IC50 6 —
CCAZGPVXKADYGB 7.3 IC50 6 —
KGPFQQPWYSPTJE 7.3 IC50 6 —
LPNSPIOOVDEVLP 7.3 IC50 6 —
MLQCGTIQCWRFKG 7.3 IC50 6 —
MRNWWQISTSVGSE 7.3 IC50 6 —
PPNDAGQUPNDRML 7.3 IC50 6 —
QHOYBSRZOHYXHP 7.3 IC50 6 —
WKUIEMLPYVVIBQ 7.3 IC50 6 —
WNLQYKOTLNFENJ 7.3 IC50 6 —
YEHUADCGMQHMIN 7.3 IC50 6 —
CNUOVJNPAJBGDE 7.2 IC50 6 —
FFKAEWHVIHHSLK 7.2 IC50 6 —
FIBNDASOWKUFPL 7.2 IC50 6 —
GVEQSOCEVMIXQZ 7.2 IC50 6 —
IFISGXQRPUCOIA 7.2 IC50 6 —
LZOXZXDSTXEKGR 7.2 IC50 6 —
NVUWOZMHNGMBRF 7.2 IC50 6 —
PHVSXWGGJQKCLX 7.2 IC50 6 —
XHBWVSJWIKUHQZ 7.2 IC50 6 —
IJVGZSADNSFGIY 7.2 IC50 6 —
ILYYQGUBBTURQO 7.2 IC50 6 —
LCWWSHWEQOZUDO 7.2 IC50 6 —
NCEMAUFPQXNRFP 7.2 IC50 6 —
UNFVPHNQVGXPKU 7.2 IC50 6 —
2D structure