Target Details
| UniProt AC | Q92800 |
|---|---|
| Gene Symbol | EZH1 |
| Protein Name | Histone-lysine N-methyltransferase EZH1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF21358 (Ezh2_MCSS) PF11616 (EZH2_WD-Binding) PF18118 (PRC2_HTH_1) PF18264 (preSET_CXC) PF00856 (SET) |
Summary
- Multi-target molecules 65
- Clinical molecules 0
- Avg pChEMBL 7.68
KEGG Pathways (3)
Active Molecules (65)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
YFLOKCLJSQKUIO
|
10.0 | IC50 | 6 | — | |
HIIQVPLDPORYGF
|
9.4 | IC50 | 5 | — | |
CHJLMVBYELJCLC
|
9.3 | IC50 | 2 | — | |
RDTWWOGVLSHQRK
|
9.3 | IC50 | 5 | — | |
GOCXRQKFPULOLE
|
9.2 | IC50 | 5 | — | |
GWWPLMJVLCHYQG
|
9.1 | IC50 | 6 | — | |
LECDCPFYHWKXQN
|
8.6 | IC50 | 6 | — | |
OGEGKWSUMBNLJE
|
8.5 | IC50 | 6 | — | |
JYHWESDDXSBHEO
|
8.5 | IC50 | 5 | — | |
QUIFNXAODBPCIP
|
8.4 | IC50 | 5 | — | |
IBJQZJITWHHCOE
|
8.4 | IC50 | 6 | — | |
NYWVSLBALKNFJR
|
8.4 | IC50 | 6 | — | |
YIDPRJWWYAEHJU
|
8.4 | IC50 | 5 | — | |
NRJPQJZSRYUTIL
|
8.4 | IC50 | 5 | — | |
FNIHSLYQEQZRHH
|
8.3 | IC50 | 5 | — | |
JFONWYWBVOYASL
|
8.3 | IC50 | 5 | — | |
ZTOAAMOSOKIAKY
|
8.2 | IC50 | 6 | — | |
HSSZJJJBEMDIKW
|
8.2 | IC50 | 5 | — | |
RNOUJORPHZOBFA
|
8.2 | IC50 | 5 | — | |
JGODQNHXSXGZBZ
|
8.2 | IC50 | 5 | — | |
QPPMMEVJOAYDNF
|
8.2 | IC50 | 6 | — | |
BCXFQOXVZKGYFG
|
8.2 | IC50 | 2 | — | |
HGVOGVKCDOMMKJ
|
8.1 | IC50 | 6 | — | |
AIFGDRAXMCFCSA
|
8.1 | IC50 | 2 | — | |
AOIZISCRIVNZJJ
|
8.1 | IC50 | 2 | — | |
HHSSNFZJCXGEOC
|
7.9 | IC50 | 2 | — | |
NXSYWBPZACPLLZ
|
7.9 | IC50 | 2 | — | |
PFHDWRIVDDIFRP
|
7.9 | IC50 | 2 | — | |
SSDRNUPMYCFXGM
|
7.9 | IC50 | 2 | — | |
AOXIOWBVFPMBOP
|
7.8 | IC50 | 2 | — | |
HSPAORFDQDFABD
|
7.8 | IC50 | 2 | — | |
YUGYQZBNPLWZEK
|
7.8 | IC50 | 2 | — | |
SLCLWGGPCPYMMD
|
7.8 | IC50 | 2 | — | |
USPSIVAZJZHYPK
|
7.7 | IC50 | 2 | — | |
FADJTYGNEWCCFM
|
7.7 | IC50 | 6 | — | |
CHJLMVBYELJCLC
|
7.7 | IC50 | 2 | — | |
BERFMMVJMKSJBI
|
7.7 | IC50 | 2 | — | |
RFMNSTSDHNUZJK
|
7.7 | IC50 | 2 | — | |
SSDRNUPMYCFXGM
|
7.6 | IC50 | 2 | — | |
VHEZDOOHAYZQOH
|
7.5 | IC50 | 2 | — | |
DPJNKUOXBZSZAI
|
7.3 | IC50 | 4 | — | |
ZOIBZSZLMJDVDQ
|
7.3 | IC50 | 2 | — | |
HPODOLXTMDHLLC
|
7.3 | IC50 | 2 | — | |
XQFINGFCBFHOPE
|
7.2 | IC50 | 3 | — | |
RXCVUHMIWHRLDF
|
7.2 | Ki | 2 | — | |
FKSFKBQGSFSOSM
|
7.1 | IC50 | 4 | — | |
ZDSWQEAIASOXHE
|
7.1 | IC50 | 2 | — | |
KBQYYXDCPRZITN
|
7.1 | IC50 | 2 | — | |
OMRNALVBPNPCDM
|
7.0 | IC50 | 2 | — | |
WCKDYPHUXUBMEB
|
7.0 | IC50 | 7 | — |