RORB — MultiTargetDB

Target Details

UniProt AC	`Q92753`
Gene Symbol	RORB
Protein Name	Nuclear receptor ROR-beta
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00104 (Hormone_recep) PF00105 (zf-C4)

Summary

Multi-target molecules 41
Clinical molecules 0
Avg pChEMBL 6.83

KEGG Pathways (1)

Circadian rhythm

Associated Diseases (1)

Idiopathic generalized epilepsies

Top Co-occurrence Targets

RORC 40 shared
RORA 3 shared
HTR2B 2 shared
PIN1 1 shared
SLC6A3 1 shared
HTR6 1 shared
NPY2R 1 shared
RXRG 1 shared
MTNR1A 1 shared
HTR5A 1 shared

Active Molecules (41)

InChIKey	pChEMBL	Type	Targets	Clinical
`GPALVRLYDQFPIU`	8.2	IC50	2	—
`FPEPDZZKOGUYFO`	8.1	IC50	2	—
`SLMOKTWBUBMWJO`	8.1	IC50	2	—
`DATNOEKWAMTIHN`	7.8	IC50	2	—
`PWNQDXFSXNJRRQ`	7.8	IC50	3	—
`MREFIIMUWJNTII`	7.6	IC50	2	—
`PSFPATVFAWGHAJ`	7.5	IC50	2	—
`VTRHQLPYGVWKKI`	7.3	IC50	2	—
`MNUCRODXGZMPCU`	7.3	IC50	3	—
`GRWNPFJXINLSNF`	7.1	IC50	2	—
`GZCDNIGGYFEPLV`	7.1	IC50	2	—
`OYCQSCPHBYKGHN`	7.0	IC50	2	—
`SHGAZHPCJJPHSC`	6.9	IC50	13	—
`ZDBJECNSNPXCFS`	6.9	IC50	2	—
`ODLLKRFSXYKRQB`	6.8	Ki	2	—
`ULYHXRTUZSKYEU`	6.8	IC50	2	—
`IORGFFCZJYGRQD`	6.8	IC50	2	—
`HCTASJAOJYRGPC`	6.8	IC50	2	—
`SBHFAQDIXHCJBY`	6.8	IC50	2	—
`DSIYRAHIZDXKRO`	6.7	IC50	2	—
`KXWLXPUSRXLJCK`	6.7	IC50	2	—
`ISWGZOZQPRMRJA`	6.7	IC50	2	—
`GZBZDZWXLLKUTQ`	6.7	IC50	2	—
`HEPPZYJPFBGTKA`	6.7	IC50	2	—
`VICVDIVPAGQTTO`	6.7	IC50	2	—
`XNZJHNCNFWAVAE`	6.7	IC50	3	—
`JFBZAEQCYPRNMQ`	6.6	Kd	2	—
`FQNXGRKEBPOPHJ`	6.6	IC50	2	—
`SPDXXZUHXTYAPT`	6.5	IC50	2	—
`KYIGOCCCBXRHNJ`	6.5	IC50	43	—
`ILXLMNLDODDHOQ`	6.4	Ki	2	—
`NSAOHDFDPAPARQ`	6.4	IC50	2	—
`QLKWBZGQDXUAPZ`	6.3	IC50	2	—
`ZBVWPYZPEXTFFC`	6.3	IC50	2	—
`FOOFCMISAIJPLF`	6.2	Kd	2	—
`VHGGVTVFPZUWCU`	6.2	Kd	2	—
`XFHHIVHARPRKCG`	6.1	IC50	2	—
`LRJKAYGDKHTSDL`	6.1	Kd	2	—
`CZZWOGGSAFJKEU`	6.0	Kd	2	—
`ZHSFCHXKHOJYIG`	6.0	IC50	2	—
`KIAHYBIZSGNTBR`	6.0	Kd	2	—