Target Details
| UniProt AC | Q92630 |
|---|---|
| Gene Symbol | DYRK2 |
| Protein Name | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) |
Summary
- Multi-target molecules 336
- Clinical molecules 6
- Avg pChEMBL 6.81
Active Molecules (336)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
DGTHPUFVPBPNPD
|
9.0 | IC50 | 3 | — | |
BQWWOBKMDWACGC
|
8.7 | IC50 | 8 | — | |
UBGUCDLLEIGHHP
|
8.7 | IC50 | 6 | — | |
HQAFQRVIFUNAKT
|
8.5 | IC50 | 3 | — | |
RYBNARZBIXTFJS
|
8.5 | IC50 | 9 | — | |
JQVRJDHSZIESJC
|
8.4 | IC50 | 2 | — | |
HPYSMRPYCUVINY
|
8.3 | IC50 | 2 | — | |
VFLDPWHFBUODDF
|
8.3 | IC50 | 25 | — | |
QHTJZFWEQYRYQE
|
8.2 | IC50 | 9 | — | |
UCULOFHOCATNHB
|
8.2 | IC50 | 2 | — | |
ZWDRSWWQYGLOOM
|
8.2 | IC50 | 2 | — | |
BWRQNVDGLTUELI
|
8.1 | IC50 | 5 | — | |
AWBAKFAKVVKANT
|
8.1 | IC50 | 2 | — | |
LCSMODPSWXEJLH
|
8.1 | IC50 | 3 | — | |
XQMMPFLQOCIGRW
|
8.1 | IC50 | 2 | — | |
LQSUUCXGVOHOFM
|
8.0 | IC50 | 2 | — | |
NMUDZNRXZXDYEQ
|
8.0 | IC50 | 9 | — | |
VCTLOEWZYIGVBO
|
8.0 | IC50 | 12 | — | |
QSGKPYRFWJINEH
|
8.0 | IC50 | 12 | — | |
AKNIGLLNHUTMPO
|
8.0 | IC50 | 9 | — | |
DPDVVGCNUWGGRS
|
8.0 | IC50 | 10 | — | |
QIYXLIZWXGGKOO
|
7.9 | IC50 | 10 | — | |
ZFOMCSNUEHMROO
|
7.9 | IC50 | 7 | — | |
KJCRALOGJOLXCU
|
7.8 | IC50 | 3 | — | |
KRWCFCQJKXIENS
|
7.8 | IC50 | 3 | — | |
MNVPCONHWCXDES
|
7.8 | IC50 | 9 | — | |
NVJVPUYRSSDOPO
|
7.8 | IC50 | 2 | — | |
QXLHPZGOJNRMDZ
|
7.8 | IC50 | 2 | — | |
PCUWPDUAQBAWHT
|
7.8 | IC50 | 4 | — | |
RJYLSCSDDDQEPD
|
7.8 | IC50 | 10 | — | |
UKLWPHGHSYZRHP
|
7.8 | IC50 | 2 | — | |
WREJZZXSNOJGIW
|
7.8 | IC50 | 9 | — | |
PZRAWCBVDRNTDQ
|
7.7 | IC50 | 2 | — | |
KAEULNCNLILYLK
|
7.7 | IC50 | 4 | — | |
PUGXENIKUPHCAF
|
7.7 | IC50 | 2 | — | |
UIARLYUEJFELEN
|
7.7 | Kd | 289 | Yes | |
ARYGGCNDASPYNG
|
7.6 | IC50 | 3 | — | |
KRXQWLCJHMDEDM
|
7.6 | IC50 | 8 | — | |
MGEGGAFJSKMJJD
|
7.6 | IC50 | 5 | — | |
VRGNMDTYOWQXQC
|
7.6 | IC50 | 8 | — | |
VRGNMDTYOWQXQC
|
7.6 | IC50 | 5 | — | |
JZCWLJDSIRUGIN
|
7.6 | Ki | 16 | — | |
CGRDYMCBGXJNLR
|
7.6 | IC50 | 9 | — | |
UYRUSUBNRZEGRJ
|
7.6 | IC50 | 2 | — | |
KHVQTEBOVFILCQ
|
7.5 | IC50 | 10 | — | |
GLXOBAUWZZUWAU
|
7.5 | IC50 | 2 | — | |
HAPIHWIYVZOFQR
|
7.5 | IC50 | 4 | — | |
QXMXIHBLICGPMG
|
7.5 | IC50 | 9 | — | |
RYBNARZBIXTFJS
|
7.5 | IC50 | 9 | — | |
WKYMGORXOQPTTO
|
7.5 | IC50 | 9 | — |