Target Details
| UniProt AC | Q8WYR1 |
|---|---|
| Gene Symbol | PIK3R5 |
| Protein Name | Phosphoinositide 3-kinase regulatory subunit 5 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF10486 (PI3K_1B_p101) |
Summary
- Multi-target molecules 297
- Clinical molecules 1
- Avg pChEMBL 6.75
KEGG Pathways (11)
- Adrenergic signaling in cardiomyocytes
- Apelin signaling pathway
- Chemokine signaling pathway
- Cholinergic synapse
- Kaposi sarcoma-associated herpesvirus infection
- Oxytocin signaling pathway
- PI3K-Akt signaling pathway
- Phospholipase D signaling pathway
- Platelet activation
- Toxoplasmosis
- cGMP-PKG signaling pathway
Associated Diseases (1)
Active Molecules (297)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
FYGDHTMAQTVJIR
|
8.2 | IC50 | 8 | — | |
BJNCOVPPPKXBBA
|
8.2 | IC50 | 8 | — | |
NLZNQTSAEGRBEQ
|
8.0 | IC50 | 8 | — | |
YWFOHQFLGQVFIB
|
8.0 | IC50 | 9 | — | |
CVJYZNKVAFBTDT
|
7.9 | IC50 | 8 | — | |
FGJSGEOFFFKFLV
|
7.9 | IC50 | 8 | — | |
NORWTLLCOTYPQA
|
7.9 | IC50 | 8 | — | |
AVPAAQMVQVGYGP
|
7.8 | IC50 | 8 | — | |
FUMQATBGDGLOKH
|
7.8 | IC50 | 8 | — | |
MGWPOIMLIUPKNZ
|
7.8 | IC50 | 8 | — | |
QXVMJULCQQDHKX
|
7.8 | IC50 | 8 | — | |
GALWNKLIQPVNFO
|
7.8 | IC50 | 8 | — | |
WJNLASRFJUMLIF
|
7.8 | IC50 | 8 | — | |
WJNLASRFJUMLIF
|
7.8 | IC50 | 8 | — | |
XJQPXTWNTSKISQ
|
7.8 | IC50 | 8 | — | |
CBLXFJOGYFFYFS
|
7.8 | IC50 | 8 | — | |
CDBZWHCUAHJXIC
|
7.8 | IC50 | 8 | — | |
PHAJRAXPUGWQRH
|
7.7 | IC50 | 8 | — | |
ADDKHACIHJBWDD
|
7.7 | IC50 | 8 | — | |
JLOYLMZLENULHD
|
7.7 | IC50 | 8 | — | |
ALMGVNBNMXRCQV
|
7.7 | IC50 | 8 | — | |
ISLVPOPCAGBKHP
|
7.7 | IC50 | 8 | — | |
UINYBYLWBAMMPE
|
7.7 | IC50 | 8 | — | |
FYGDHTMAQTVJIR
|
7.7 | IC50 | 8 | — | |
YWWOQYKAYFXXAB
|
7.7 | IC50 | 8 | — | |
KBOCINOJPQBJHY
|
7.6 | IC50 | 8 | — | |
NYRRAVJTVDFZLN
|
7.6 | IC50 | 8 | — | |
VDKPPWNYXRVYDM
|
7.6 | IC50 | 8 | — | |
BDQJIUXJPAJLOX
|
7.6 | IC50 | 8 | — | |
LUKHPIFOJUBBBW
|
7.6 | IC50 | 8 | — | |
MAVPREISACEICP
|
7.6 | IC50 | 8 | — | |
NLZNQTSAEGRBEQ
|
7.6 | IC50 | 8 | — | |
WHLHMMULLULBDZ
|
7.6 | IC50 | 8 | — | |
DNYROFWYJBYUMQ
|
7.6 | IC50 | 8 | — | |
FHCPWFJAEYLMGM
|
7.5 | IC50 | 8 | — | |
JGMSAJQEYJEURV
|
7.5 | IC50 | 8 | — | |
GXTWTBFETNXESR
|
7.5 | IC50 | 8 | — | |
LINCHXKNCSPOKA
|
7.5 | IC50 | 8 | — | |
AYRHYIQWAHXGQS
|
7.5 | IC50 | 8 | — | |
MPWLFBVAYNHZHQ
|
7.5 | IC50 | 8 | — | |
FUMQATBGDGLOKH
|
7.5 | IC50 | 8 | — | |
AHAJAAGFYQHYMQ
|
7.5 | IC50 | 8 | — | |
BDQJIUXJPAJLOX
|
7.5 | IC50 | 8 | — | |
FUMQATBGDGLOKH
|
7.5 | IC50 | 8 | — | |
XDNGIZBMMIZNGD
|
7.4 | IC50 | 8 | — | |
XJQPXTWNTSKISQ
|
7.4 | IC50 | 8 | — | |
AVYIJPUHWYOVRO
|
7.4 | IC50 | 8 | — | |
YWWOQYKAYFXXAB
|
7.4 | IC50 | 8 | — | |
LBXKRIWHCRXGHJ
|
7.4 | IC50 | 8 | — | |
KPFIPJMXDOSFKZ
|
7.4 | IC50 | 8 | — |