Target Details
| UniProt AC | Q8WW43 |
|---|---|
| Gene Symbol | APH1B |
| Protein Name | Gamma-secretase subunit APH-1B |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF06105 (Aph-1) |
Summary
- Multi-target molecules 1,927
- Clinical molecules 1
- Avg pChEMBL 7.37
KEGG Pathways (3)
Active Molecules (1,927)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
KDLJOGLRFSSOAE
|
8.7 | IC50 | 6 | — | |
FXJUXKWZBMDVAH
|
8.6 | IC50 | 6 | — | |
IRDXXXQQURUGJA
|
8.6 | IC50 | 6 | — | |
KIUCLWXKKIMRFD
|
8.6 | IC50 | 6 | — | |
URHOPXMUZHWVON
|
8.6 | IC50 | 6 | — | |
LZCMGTZILVEQAQ
|
8.6 | IC50 | 7 | — | |
VGXKDVILUDFEGF
|
8.6 | IC50 | 6 | — | |
ITBUGKSWVOSSJM
|
8.6 | IC50 | 6 | — | |
KKKLWLSGVSXCDO
|
8.6 | IC50 | 8 | — | |
OEDGPKOJXFRUSK
|
8.6 | IC50 | 6 | — | |
DIAWNMMXXFCLKG
|
8.6 | IC50 | 6 | — | |
IFSWJYDDFODZGS
|
8.6 | IC50 | 6 | — | |
MPXNYRBVXQWUHY
|
8.6 | IC50 | 6 | — | |
LPGNFEMHCAETQT
|
8.6 | IC50 | 6 | — | |
XCQZOSJEXBZVBN
|
8.6 | IC50 | 6 | — | |
QSHGISMANBKLQL
|
8.6 | IC50 | 6 | — | |
CTFWPCUEANDSTG
|
8.6 | IC50 | 6 | — | |
BPHSGFNDDBHOCL
|
8.5 | IC50 | 6 | — | |
KSECKJGIGTVRJF
|
8.5 | IC50 | 6 | — | |
NYGIJFDXYBHSLD
|
8.5 | IC50 | 6 | — | |
PNXPIAZNJOCKLW
|
8.5 | IC50 | 6 | — | |
PPAVFGFEUHBOOI
|
8.5 | IC50 | 6 | — | |
VILRXGUHYYSGJD
|
8.5 | IC50 | 6 | — | |
AFKBLOZTLRRCHH
|
8.5 | IC50 | 6 | — | |
BHMZKSMLPYGIEY
|
8.5 | IC50 | 6 | — | |
DVNZULBMBBBODA
|
8.5 | IC50 | 6 | — | |
IDSIFGQKRCZJMK
|
8.5 | IC50 | 6 | — | |
GLGMXPHOJFVYGX
|
8.5 | IC50 | 6 | — | |
LAWTYRZCFAJQLA
|
8.5 | IC50 | 6 | — | |
SWRVIVLGYFWSGN
|
8.5 | IC50 | 6 | — | |
LXSSZLZYQWQDEU
|
8.5 | IC50 | 6 | — | |
SHSQQWJYNQVTHA
|
8.5 | IC50 | 6 | — | |
NNLOMIQJKYIBQF
|
8.5 | IC50 | 6 | — | |
YUDLYERAJUOPAX
|
8.5 | IC50 | 6 | — | |
ADXBEEAHQAXNTH
|
8.5 | IC50 | 6 | — | |
URHOPXMUZHWVON
|
8.5 | IC50 | 6 | — | |
VWJNTABGGSLZMQ
|
8.5 | IC50 | 6 | — | |
AUHIFWMBYZBSOK
|
8.5 | IC50 | 6 | — | |
IYODMMGZTGSKGN
|
8.5 | IC50 | 6 | — | |
KKKLWLSGVSXCDO
|
8.5 | IC50 | 6 | — | |
HSJXMFJMCVMAKI
|
8.4 | IC50 | 6 | — | |
IOFFAAZPTYLRCR
|
8.4 | IC50 | 6 | — | |
IRYDPZOKPJBEFP
|
8.4 | IC50 | 6 | — | |
FEZIWNSYTANXFR
|
8.4 | IC50 | 6 | — | |
INPIJMMJIYSUTN
|
8.4 | IC50 | 6 | — | |
YQNSNYJLKVSHGQ
|
8.4 | IC50 | 6 | — | |
AXUCGPSYXKJACT
|
8.4 | IC50 | 8 | — | |
COGPSDSDJBWMRQ
|
8.4 | IC50 | 6 | — | |
DDVJBUDKFFSDRR
|
8.4 | IC50 | 6 | — | |
DIYNYEGNVUSOIR
|
8.4 | IC50 | 7 | — |