Target Details
UniProt ACQ8WQX9
Gene SymbolPDEB1
Protein NamePhosphodiesterase
OrganismTrypanosoma brucei
Entry Name
Organism Category Pathogen
Pfam Domains PF01590 (GAF) PF00233 (PDEase_I)
UniProt
Summary
  • Multi-target molecules 68
  • Clinical molecules 0
  • Avg pChEMBL 6.84
Top Co-occurrence Targets
Active Molecules (68)
InChIKey pChEMBL Type Targets Clinical
OKHIBGYAOMMETC 8.5 IC50 2 —
DNDNLFXKQSTINI 8.4 IC50 5 —
DNDNLFXKQSTINI 8.4 IC50 5 —
DNDNLFXKQSTINI 8.4 IC50 4 —
ARSHVDLLDUTOKJ 8.0 IC50 2 —
FLCHWTIQFVHCMK 7.9 IC50 2 —
FZHQFKLHOFLUQF 7.8 IC50 2 —
BLRZNXZBGGTDMQ 7.7 Ki 2 —
SEVYDVWEYJOUSZ 7.6 Ki 2 —
JTKHZHDPXJBJRV 7.5 Ki 2 —
SZFCSSMZLOVLEY 7.4 Ki 2 —
VRSCGUCAJHMOSB 7.4 Ki 2 —
DZMHUZHTZIODAZ 7.4 Ki 2 —
JPXAIORZGBCHIB 7.3 IC50 5 —
VZKJWTFPORBEEH 7.2 Ki 2 —
IQLZSZSHNQVOIB 7.2 Ki 2 —
VKKBQXCHEXHWOL 7.1 Ki 2 —
QCQZBFMOPHFNOO 7.1 Ki 2 —
NKSAGCMERZDMGS 7.1 Ki 2 —
PRXHKALDWKQKHD 7.0 Ki 2 —
FSRZUYDPEQEWCU 7.0 Ki 2 —
MEOGYVPRZOVECA 7.0 Ki 2 —
JBXZRZAKTBXTGR 7.0 Ki 2 —
KQHCKOSDQJMVFO 7.0 Ki 2 —
WDBGQRYJBPYOHH 7.0 Ki 2 —
UBSNEJXDHUCVPQ 7.0 Ki 2 —
PDEOFJKNCBPJSR 7.0 Ki 2 —
CNKULZYKNGMIIR 7.0 Kd 3 —
HULDHLXFTKLQFB 6.9 Ki 2 —
VNKHPMYYXSARFF 6.9 Ki 2 —
WLMAJVYCIWOYDU 6.9 Ki 2 —
DOJRVSYOJAVHFU 6.8 Ki 2 —
ZZLCRCARUBASNA 6.8 Ki 2 —
FLXJAXHKQHLPKX 6.7 Ki 2 —
ONAYELXCEIVZIA 6.7 Ki 2 —
YSVRRKKYMUNGCQ 6.7 Ki 2 —
DCAMOMXGWITYCV 6.6 Ki 2 —
UAHRMESTJPCBFW 6.6 Ki 2 —
QMLOEDCWTHEZJY 6.6 IC50 5 —
TZSRFHRXKKCOOX 6.6 Ki 2 —
OTBLMOBBDWRQQX 6.5 Ki 2 —
DCEPOKVHEWRTDS 6.5 Ki 2 —
NZTAZJDYGSXAMS 6.5 IC50 2 —
PSEOWXHNKGQICS 6.5 IC50 2 —
QNGCEEKDIHUHQH 6.5 Ki 2 —
RLKPXYFPWXJUPQ 6.5 Ki 2 —
UAIXEGFVIVPDNH 6.5 Ki 2 —
SOFFPXUEJHXWFX 6.5 Ki 2 —
JNDNVCXYXKMMTQ 6.4 Ki 2 —
QBSSMBQSBXGATC 6.4 Ki 2 —
2D structure