Target Details
| UniProt AC | Q8NB16 |
|---|---|
| Gene Symbol | MLKL |
| Protein Name | Mixed lineage kinase domain-like protein |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF22215 (MLKL_N) PF07714 (PK_Tyr_Ser-Thr) |
Summary
- Multi-target molecules 254
- Clinical molecules 0
- Avg pChEMBL 8.27
KEGG Pathways (4)
Active Molecules (254)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
SNRUTMWCDZHKKM
|
6.3 | Kd | 4 | — | |
IVVSBEQDCAZLFY
|
6.0 | IC50 | 333 | — | |
KHVVJKLNKLQLJZ
|
6.0 | IC50 | 288 | — | |
MAHFVAHPQSLLJF
|
6.0 | IC50 | 288 | — |