Target Details
UniProt ACQ8NB16
Gene SymbolMLKL
Protein NameMixed lineage kinase domain-like protein
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF22215 (MLKL_N) PF07714 (PK_Tyr_Ser-Thr)
UniProt
Summary
  • Multi-target molecules 254
  • Clinical molecules 0
  • Avg pChEMBL 8.27
KEGG Pathways (4)
Top Co-occurrence Targets
Active Molecules (254)
InChIKey pChEMBL Type Targets Clinical
JRUKWWHAQPEKAA 8.5 IC50 2 —
SQJPCTAGKZBIIZ 8.5 IC50 2 —
UGQKUBUQYPHWQD 8.5 IC50 2 —
WHVHKBUPSUSYAL 8.5 IC50 2 —
TZXYDNQUSBJURA 8.4 IC50 2 —
FHMPYPIPCWQXEJ 8.4 IC50 2 —
LWGOFWWGJAJUKJ 8.4 IC50 2 —
MEIRWDCGNCYHGJ 8.4 IC50 2 —
MEIRWDCGNCYHGJ 8.4 IC50 2 —
OOHWXVMNYAIFBU 8.4 IC50 2 —
RGPRFYTUFVLMEL 8.4 IC50 2 —
AYEGXXOXIOWXCD 8.4 IC50 2 —
COCLXHBFUGZJBI 8.4 IC50 2 —
IUSXFQNTDSJZSX 8.4 IC50 2 —
DNWHHGJZSGNIPU 8.4 IC50 2 —
JBHRNPLTGWTGHX 8.4 IC50 2 —
SHJHUJPYBYTPPG 8.4 IC50 2 —
YSBWBLIHHMJTAY 8.4 IC50 2 —
IBZKREARIHWPAX 8.4 IC50 2 —
MRYPBXQDXGBARZ 8.4 IC50 2 —
XUZTUIGKADFQTD 8.4 IC50 2 —
AVNYULWTERJTEY 8.4 IC50 2 —
MRYPBXQDXGBARZ 8.4 IC50 2 —
FQTJUEYKGHZUES 8.3 IC50 2 —
NKNSMRWBHMCQTM 8.3 IC50 2 —
NXCZMDQVFMPBOI 8.3 IC50 2 —
TZXYDNQUSBJURA 8.3 IC50 2 —
ZJEITEDIBHPUSP 8.3 IC50 2 —
IKYVVXPGERUFKR 8.3 IC50 2 —
NXCZMDQVFMPBOI 8.3 IC50 2 —
RCLQRRIIUCBMPX 8.3 IC50 2 —
XZBGRGYKTKCJDO 8.3 IC50 2 —
ALAZXNZFIANJMN 8.3 IC50 2 —
GVNGLGMOHLFLJG 8.3 IC50 2 —
HKDBKENBVSIISE 8.3 IC50 2 —
KNIULYCUWOGHSI 8.3 IC50 2 —
RVGCSKSAZFLLMP 8.3 IC50 2 —
XUZTUIGKADFQTD 8.3 IC50 2 —
WHVHKBUPSUSYAL 8.3 IC50 2 —
WTNYOVMWJWLLIQ 8.3 IC50 2 —
XCTMAPWBKRRVPM 8.3 IC50 2 —
RGPRFYTUFVLMEL 8.3 IC50 2 —
XUZTUIGKADFQTD 8.3 IC50 2 —
AIGWTZNVNIYEJA 8.3 IC50 2 —
FNRCSGQLGPGABP 8.3 IC50 2 —
GRNPQAUIFHUTSP 8.3 IC50 2 —
SHJHUJPYBYTPPG 8.3 IC50 2 —
ATMWMZOSKFLIGS 8.3 IC50 2 —
FDJIJMTZXHXLBI 8.2 IC50 2 —
XYVQOYARHKRTFN 8.2 IC50 2 —
2D structure