Target Details
| UniProt AC | Q7KZI7 |
|---|---|
| Gene Symbol | MARK2 |
| Protein Name | Serine/threonine-protein kinase MARK2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF02149 (KA1) PF00069 (Pkinase) PF00627 (UBA) |
Summary
- Multi-target molecules 133
- Clinical molecules 16
- Avg pChEMBL 6.68
Associated Diseases (1)
Active Molecules (133)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
HKSZLNNOFSGOKW
|
9.8 | Kd | 408 | — | |
HKSZLNNOFSGOKW
|
9.2 | Kd | 213 | — | |
OFIFLUFVENTCNZ
|
8.7 | IC50 | 11 | — | |
OSVUGUHRKMMBSE
|
8.5 | Kd | 170 | — | |
NXSJMRCTGYTSTK
|
8.2 | Kd | 200 | — | |
HKSZLNNOFSGOKW
|
8.1 | Ki | 118 | — | |
PBCZSGKMGDDXIJ
|
7.9 | Kd | 68 | Yes | |
UIARLYUEJFELEN
|
7.8 | Kd | 289 | Yes | |
ZCCPLJOKGAACRT
|
7.8 | Kd | 599 | — | |
CFIBXVQLBVNOHW
|
7.8 | Ki | 64 | — | |
FLEAYYMORDPWAJ
|
7.8 | Ki | 90 | — | |
MWKSRKSEWLRPBL
|
7.7 | Kd | 1075 | — | |
VWVYILCFSYNJHF
|
7.6 | Ki | 49 | — | |
MVJMMLFMPWITEJ
|
7.4 | Ki | 110 | — | |
ZCCJKVBTHCOISJ
|
7.4 | Ki | 46 | — | |
QQWUGDVOUVUTOY
|
7.4 | Kd | 231 | Yes | |
LRZYYIZFBXFSJB
|
7.3 | Ki | 69 | — | |
NFKMFNBKEOQNPZ
|
7.3 | Ki | 43 | — | |
XYZNKCSDQRKAFR
|
7.3 | Ki | 53 | — | |
UKBGBACORPRCGG
|
7.3 | IC50 | 17 | — | |
GCYXEGSPUDSZJY
|
7.2 | Ki | 82 | — | |
UDFDIIVNIYWXDM
|
7.2 | Ki | 74 | — | |
XKFTZKGMDDZMJI
|
7.2 | Ki | 56 | — | |
BSFNGHCTZDCQBF
|
7.1 | Ki | 93 | — | |
DASFSPDIWCMVRW
|
7.1 | Ki | 21 | — | |
DBXGGXLBTWZXBB
|
7.1 | Ki | 39 | — | |
HEUSUIRCBWROMH
|
7.1 | Ki | 64 | — | |
JPOSFPUHBHRUAX
|
7.1 | Ki | 40 | Yes | |
PCQMERRARZKTPW
|
7.1 | Ki | 68 | — | |
RJZDECGDCKOHBV
|
7.1 | Ki | 70 | — | |
UMTWTCVTRDYHQQ
|
7.1 | Ki | 56 | — | |
ZWVZORIKUNOTCS
|
7.1 | Ki | 69 | — | |
AILRADAXUVEEIR
|
7.0 | IC50 | 75 | — | |
BMGQWWVMWDBQGC
|
7.0 | Kd | 147 | Yes | |
BMGQWWVMWDBQGC
|
7.0 | Kd | 91 | Yes | |
AYCPARAPKDAOEN
|
6.9 | Kd | 73 | — | |
FONINLXADYUZFI
|
6.9 | Ki | 25 | — | |
PIQCTGMSNWUMAF
|
6.9 | Ki | 137 | Yes | |
XUZMWHLSFXCVMG
|
6.9 | Kd | 24 | — | |
DFMCXVONDDGQIY
|
6.8 | Ki | 66 | — | |
KKYPRNBBPBRJQX
|
6.8 | Ki | 40 | — | |
MCCCQFAOMZMZKE
|
6.8 | Ki | 52 | — | |
YWTBGJGMTBHQTM
|
6.8 | Ki | 65 | — | |
ALKJNCZNEOTEMP
|
6.7 | Kd | 55 | — | |
AWDORCFLUJZUQS
|
6.7 | Ki | 22 | — | |
DKSNLQYRZJKYOC
|
6.7 | Ki | 51 | — | |
IJNGXROUMFEKDB
|
6.7 | Ki | 39 | — | |
PSCJSWRVCKUMSL
|
6.7 | Ki | 35 | — | |
WINHZLLDWRZWRT
|
6.7 | Ki | 66 | — | |
XSDJOIOVIMPMHD
|
6.7 | Ki | 44 | — |