Target Details
| UniProt AC | Q76MJ5 |
|---|---|
| Gene Symbol | ERN2 |
| Protein Name | Serine/threonine-protein kinase/endoribonuclease IRE2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) PF06479 (Ribonuc_2-5A) |
Summary
- Multi-target molecules 8
- Clinical molecules 2
- Avg pChEMBL 6.79
Active Molecules (8)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
HKSZLNNOFSGOKW
|
7.7 | IC50 | 408 | — | |
BEMXNPOYLRULNU
|
7.5 | IC50 | 2 | — | |
BFSMGDJOXZAERB
|
6.9 | Kd | 33 | — | |
BVFULXSORCNDGZ
|
6.9 | IC50 | 2 | — | |
PZDLYSIDAYGDSJ
|
6.7 | IC50 | 2 | — | |
UIARLYUEJFELEN
|
6.5 | Kd | 289 | Yes | |
KOZFSFOOLUUIGY
|
6.0 | Kd | 88 | Yes | |
UQRCJCNVNUFYDX
|
6.0 | Kd | 27 | — |