Target Details
UniProt ACQ5VT25
Gene SymbolCDC42BPA
Protein NameSerine/threonine-protein kinase MRCK alpha
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00130 (C1_1) PF00780 (CNH) PF08826 (DMPK_coil) PF15796 (KELK) PF25346 (PH_MRCK) PF00069 (Pkinase) PF00433 (Pkinase_C)
UniProt
Summary
  • Multi-target molecules 233
  • Clinical molecules 60
  • Avg pChEMBL 7.87
Top Co-occurrence Targets
Active Molecules (233)
InChIKey pChEMBL Type Targets Clinical
YTWFPZPOMPBTKV 11.3 Ki 4 —
UELSMLDRSQFVHG 10.8 Ki 4 —
BOJODXOBEKPFNV 10.8 Ki 4 —
OTJJLFCJBNJDPE 10.7 Ki 4 —
LUJJOIFRFNRBGY 10.7 Ki 4 —
WOFYXBWCKCYGFB 10.6 Ki 4 —
BTNHOAWDPXMJLS 10.5 Ki 4 —
CYLSXYAMTHBWRF 10.5 Ki 4 —
HIPZYNPZNXJDEM 10.5 Ki 4 —
HHGYNBXPZXZDBW 10.4 Ki 4 —
GRFYVFBPFKGUQO 10.4 Ki 4 —
ADUXONXETMHODJ 10.3 Ki 4 —
JKSGUMBEZZQFIM 10.3 Ki 4 —
MWLZXNZGOYNQQD 10.2 Ki 4 —
GZVUGIYFFYQNCJ 10.2 Ki 4 —
JQHSLDZAVPJKFZ 10.1 Ki 4 —
WVKCMVMISLIFTD 10.0 Ki 4 —
JUDDACYFKPQFQQ 10.0 Ki 4 —
RJKFOVLPORLFTN 10.0 pIC50 10 Yes
NCJKEBUDZLRUMX 9.9 Ki 3 —
GZNJCPGGBJUQMM 9.9 Ki 4 —
RCYRZAXLGQJUBN 9.8 Ki 4 —
PAKGCPHHMNPWAU 9.8 Ki 4 —
SWQDUVOIJJCWIG 9.7 Ki 4 —
BMMXFLCCJJRAMC 9.7 Ki 4 —
KDBDEJFJWFXSGJ 9.7 Ki 4 —
QGNSDSWZRBYLIU 9.7 Ki 4 —
GJMNAFGEUJBOCE 9.7 pIC50 5 Yes
AQBIAGJFJKMCNG 9.7 Ki 4 —
RDYKOKLXJDAPAA 9.7 Ki 3 —
ODXYBJZMEVDVSA 9.7 Ki 4 —
FOQWCNLMJDIHMR 9.6 Ki 4 —
LMNVPKCUVZQIRI 9.6 Ki 4 —
SFSGZVUHYWMYSL 9.6 Ki 3 —
ZLPABBNBKHSAKV 9.6 Ki 4 —
GCHWCYMGCVYULP 9.5 Ki 4 —
DZSWYUCCPNQWOQ 9.4 Ki 4 —
XNAZVKJDUOIJBC 9.4 Ki 4 —
WNRXXFMGMKLIHP 9.4 pIC50 5 Yes
WCWNFANFHMNQEP 9.4 pIC50 7 Yes
GSWIVOZTNMRYES 9.3 Ki 3 —
XFZYXYYYAMPVQK 9.3 Ki 2 —
SFYDDYYDYNGHOA 9.3 Ki 4 —
RTAMKRDNYWGAPQ 9.3 Ki 4 —
TUVDKYUMPUMBSY 9.2 Ki 3 —
GASKYZOWZMIJOP 9.2 Ki 4 —
ILICDTROWKQZEN 9.2 Ki 3 —
OLKPRWFWMGMGCJ 9.2 Ki 4 —
MIONXARKYZYLSX 9.2 Ki 4 —
HTCMKQLSSZWFTP 9.2 pIC50 5 Yes
2D structure