Target Details
| UniProt AC | Q54A96 |
|---|---|
| Gene Symbol | dhod |
| Protein Name | Dihydroorotate dehydrogenase (quinone), mitochondrial |
| Organism | Plasmodium falciparum |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF01180 (DHO_dh) |
Summary
- Multi-target molecules 73
- Clinical molecules 0
- Avg pChEMBL 6.82
Active Molecules (73)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RHZLPWXPGLGMLM
|
8.6 | Ki | 2 | — | |
NLEHXOQPQQDQBB
|
8.0 | IC50 | 2 | — | |
KKCBTRGIGVWQFK
|
8.0 | IC50 | 2 | — | |
JEEOGRYTTNEULC
|
7.8 | IC50 | 2 | — | |
HOTDSHUZUQSKJD
|
7.7 | IC50 | 2 | — | |
OIZSVTOIBNSVOS
|
7.7 | IC50 | 2 | — | |
DJWKVIKEQRMJEF
|
7.7 | IC50 | 2 | — | |
PHPXBFMLYCJALY
|
7.5 | IC50 | 2 | — | |
OFUZRRSLIRZBNG
|
7.5 | IC50 | 2 | — | |
UJADSHNYKLSXNU
|
7.5 | IC50 | 2 | — | |
CUCVTDOXQYMYKL
|
7.4 | IC50 | 2 | — | |
RIOPTIZLYYUGNM
|
7.4 | IC50 | 2 | — | |
WPVMVODGPNYYEV
|
7.4 | IC50 | 2 | — | |
XRXYHTFKWSMTFI
|
7.4 | IC50 | 2 | — | |
QDOYRUBXBHREAH
|
7.3 | IC50 | 2 | — | |
OXYDLVAOXASTMW
|
7.2 | IC50 | 2 | — | |
ACFOZQUWTKSSQQ
|
7.2 | IC50 | 2 | — | |
HLJDHIBNAUEZQQ
|
7.2 | IC50 | 2 | — | |
OQYMMMMIAASALW
|
7.2 | IC50 | 3 | — | |
PYAJSQKAKKJIPC
|
7.1 | IC50 | 2 | — | |
RRBKDKSQWXVXTA
|
7.1 | IC50 | 2 | — | |
YGZFJEKSLROESA
|
7.1 | IC50 | 2 | — | |
YLMPCKDYBHCDDQ
|
7.1 | IC50 | 2 | — | |
WZYJDNGSKRVUPE
|
7.1 | IC50 | 2 | — | |
AHTZIFIBNCSFEG
|
7.1 | IC50 | 3 | — | |
IJQRIJIMSCXKII
|
7.0 | IC50 | 2 | — | |
JFTBSVDVJGSVIE
|
7.0 | IC50 | 2 | — | |
KOKPPSWBLFTOPX
|
7.0 | IC50 | 2 | — | |
PVEPMZABJVMJCU
|
7.0 | IC50 | 2 | — | |
WGKJHZFPPGJYME
|
7.0 | IC50 | 2 | — | |
VYVPDPXTAPGXSK
|
7.0 | IC50 | 2 | — | |
IAAZASDRCXBBAZ
|
6.9 | IC50 | 2 | — | |
ATRMCGMFUQBVPN
|
6.8 | IC50 | 2 | — | |
TZMPAXWVWBRVRY
|
6.8 | IC50 | 2 | — | |
CEZYGDRWJZTHFD
|
6.8 | IC50 | 2 | — | |
LUBYVMXKSAURLT
|
6.8 | IC50 | 2 | — | |
NKIJNFMSYDSAJK
|
6.8 | IC50 | 2 | — | |
QKTRQKWOYXJVQT
|
6.8 | IC50 | 2 | — | |
BWISZTGNXTUWEB
|
6.7 | IC50 | 2 | — | |
NLLKFJJPILZNOG
|
6.7 | IC50 | 2 | — | |
ZCCJUZIRKRMTMO
|
6.7 | IC50 | 2 | — | |
FWEMUPBSFQCOSI
|
6.6 | IC50 | 2 | — | |
RNLKPTOJCXLFDG
|
6.6 | IC50 | 3 | — | |
SSUWIKHINXMVLA
|
6.6 | IC50 | 2 | — | |
LRHHXKBKRNNFRV
|
6.6 | IC50 | 2 | — | |
BYCMCIFIKZHIRR
|
6.5 | IC50 | 2 | — | |
VPYGCGLFZVMTRP
|
6.5 | IC50 | 2 | — | |
OMQCQQGZRWJBCI
|
6.5 | IC50 | 2 | — | |
BLBSNYYRLAWWDS
|
6.5 | IC50 | 3 | — | |
VSQZAFNNCVYGIM
|
6.5 | IC50 | 2 | — |