Target Details
| UniProt AC | Q46991 |
|---|---|
| Gene Symbol | imiA |
| Protein Name | beta-lactamase |
| Organism | Enterobacter cloacae |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF13354 (Beta-lactamase2) |
Summary
- Multi-target molecules 5
- Clinical molecules 0
- Avg pChEMBL 7.52
Top Co-occurrence Targets
- bla 4 shared
- ccrA 4 shared
- ampC 4 shared
- KPC-2 1 shared
- blaUOE-1 1 shared
- bla OXY 1 shared
- blaTEM-1 1 shared
- blaTEM-125 1 shared
- 1 shared
- blaCTX-M-53 1 shared
Active Molecules (5)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MTRYCRPKNWRHLE
|
8.1 | IC50 | 4 | — | |
KODABZGSORMKQV
|
7.5 | IC50 | 4 | — | |
LPQZKKCYTLCDGQ
|
7.5 | IC50 | 15 | — | |
YJSNNWLWFJHTLH
|
7.3 | IC50 | 4 | — | |
XFARUGBBAMTOCU
|
7.1 | IC50 | 4 | — |