Target Details
| UniProt AC | Q27783 |
|---|---|
| Gene Symbol | N/A |
| Protein Name | Bifunctional dihydrofolate reductase-thymidylate synthase |
| Organism | Trypanosoma brucei brucei |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF00186 (DHFR_1) PF00303 (Thymidylat_synt) |
Summary
- Multi-target molecules 3
- Clinical molecules 0
- Avg pChEMBL 8.78
Top Co-occurrence Targets
- DHFR 3 shared
Active Molecules (3)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ULOUWSHZZVXAHK
|
9.1 | IC50 | 2 | — | |
NLZHOJOCWCLWFT
|
8.7 | IC50 | 2 | — | |
XRRABFIIRGELKS
|
8.6 | IC50 | 2 | — |