Target Details
| UniProt AC | Q16822 |
|---|---|
| Gene Symbol | PCK2 |
| Protein Name | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00821 (PEPCK_GTP) PF17297 (PEPCK_N) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 6.38
KEGG Pathways (13)
- AMPK signaling pathway
- Adipocytokine signaling pathway
- Citrate cycle (TCA cycle)
- FoxO signaling pathway
- Glucagon signaling pathway
- Glycolysis / Gluconeogenesis
- Insulin resistance
- Insulin signaling pathway
- Metabolic pathways
- PI3K-Akt signaling pathway
- PPAR signaling pathway
- Proximal tubule bicarbonate reclamation
- Pyruvate metabolism
Associated Diseases (1)
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ZCCPLJOKGAACRT
|
6.4 | Kd | 599 | — | |
MWKSRKSEWLRPBL
|
6.4 | Kd | 1075 | — |