Target Details
| UniProt AC | Q16654 |
|---|---|
| Gene Symbol | PDK4 |
| Protein Name | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF10436 (BCDHK_Adom3) PF02518 (HATPase_c) |
Summary
- Multi-target molecules 381
- Clinical molecules 0
- Avg pChEMBL 6.84
KEGG Pathways (1)
Active Molecules (381)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
IAMXTOFVAQFWAG
|
7.7 | IC50 | 4 | — | |
GJIDOEDDEGPTSO
|
7.7 | IC50 | 4 | — | |
LYPDEIQDNUKHGB
|
7.7 | IC50 | 4 | — | |
UTZSWEGCKNIASP
|
7.7 | IC50 | 4 | — | |
ZZYMTFSRMGVTHN
|
7.7 | IC50 | 4 | — | |
RAPGJWJWLNLLJV
|
7.6 | IC50 | 4 | — | |
YZHKJZDQIGUOAK
|
7.6 | IC50 | 2 | — | |
ZSRDAOYQIHISJX
|
7.5 | IC50 | 4 | — | |
ZBWLUANTWWXFAY
|
7.5 | IC50 | 4 | — | |
FIEODOYVCMKNJZ
|
7.5 | IC50 | 2 | — | |
SRCSURSLBOIZMP
|
7.5 | IC50 | 4 | — | |
TYTXGPAMIGYEGN
|
7.5 | IC50 | 4 | — | |
RANQSIYIJYBQSV
|
7.5 | IC50 | 4 | — | |
NXCCFZKYCZDCMZ
|
7.4 | IC50 | 2 | — | |
FKRPRKAKBURXTN
|
7.3 | IC50 | 4 | — | |
RTYCQDBBCMTUFF
|
7.3 | IC50 | 4 | — | |
SFQMDVJNIAAAJA
|
7.3 | IC50 | 4 | — | |
PHZKSLPIUQGPAT
|
7.2 | IC50 | 2 | — | |
SRAUODURYYKAAX
|
7.2 | IC50 | 4 | — | |
CYJUFMHEEQFJAT
|
7.2 | IC50 | 6 | — | |
WTNCKLVOKCXDAU
|
7.2 | IC50 | 4 | — | |
MUBBTSZWDVFVLT
|
7.2 | IC50 | 3 | — | |
XRMAIQZIMRILDM
|
7.2 | IC50 | 4 | — | |
DZNOYNAVIGLCIO
|
7.2 | IC50 | 4 | — | |
VDUOAOAXBCEYSN
|
7.1 | IC50 | 4 | — | |
JAXMQOAWBPDQGA
|
7.1 | IC50 | 4 | — | |
JAXMQOAWBPDQGA
|
7.1 | IC50 | 4 | — | |
NDRMBCNSTDAADS
|
7.1 | IC50 | 4 | — | |
CQPMMSAANJNLLH
|
7.1 | IC50 | 4 | — | |
OXQTXJIDMWRZLX
|
7.1 | IC50 | 4 | — | |
VRUHOUHYPBCHJF
|
7.1 | IC50 | 4 | — | |
VJSMYBWGSKJUEL
|
7.1 | IC50 | 4 | — | |
XPOQCGFJEGWPCZ
|
7.1 | IC50 | 4 | — | |
CFKHTEWRARJPEJ
|
7.0 | IC50 | 4 | — | |
XTPBKJJFRXGTTG
|
7.0 | IC50 | 4 | — | |
WFJUFNKDUQHULP
|
7.0 | IC50 | 4 | — | |
ADSGNVVPFOHZGF
|
7.0 | IC50 | 4 | — | |
ADYFSAHHBUQVGK
|
7.0 | IC50 | 4 | — | |
AEROUCXDUDYEKO
|
7.0 | IC50 | 4 | — | |
APWMGNIAYJJUAF
|
7.0 | IC50 | 4 | — | |
ARUCEZREJLJFDT
|
7.0 | IC50 | 4 | — | |
BCJWSMLGFKGOGY
|
7.0 | IC50 | 4 | — | |
BEDBXCKARVIOCD
|
7.0 | IC50 | 4 | — | |
BPZOUMFIFRETCA
|
7.0 | IC50 | 4 | — | |
BQUDNQLXMYGDNQ
|
7.0 | IC50 | 4 | — | |
BSLIZBUPULPNHQ
|
7.0 | IC50 | 4 | — | |
BSLIZBUPULPNHQ
|
7.0 | IC50 | 4 | — | |
BSQGGNPQVHKELV
|
7.0 | IC50 | 4 | — | |
BYSDPXBOYDDWFZ
|
7.0 | IC50 | 4 | — | |
CAIPBEZKRVGEKE
|
7.0 | IC50 | 4 | — |