Target Details
| UniProt AC | Q15078 |
|---|---|
| Gene Symbol | CDK5R1 |
| Protein Name | Cyclin-dependent kinase 5 activator 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF03261 (CDK5_activator) |
Summary
- Multi-target molecules 891
- Clinical molecules 54
- Avg pChEMBL 6.92
KEGG Pathways (3)
Active Molecules (891)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ARIOBGGRZJITQX
|
9.7 | IC50 | 24 | — | |
KKNXJZMTIWJEEF
|
9.7 | IC50 | 4 | — | |
FONDNEXKEYTNCS
|
9.2 | IC50 | 4 | — | |
LUWQTRGZKXLDSO
|
9.2 | IC50 | 11 | — | |
MLZPRAPIZUZUNO
|
9.2 | IC50 | 4 | — | |
OUCDNSRNVVOKPA
|
9.2 | IC50 | 4 | — | |
SMUQLRPBIZRLKK
|
9.2 | IC50 | 4 | — | |
DQBASRYERZQRJJ
|
9.1 | IC50 | 15 | — | |
HRKCERYJQXATNH
|
9.1 | IC50 | 11 | — | |
OYWQYSATLUKKCZ
|
9.1 | IC50 | 4 | — | |
PHVGAEJTLZFYTO
|
9.1 | IC50 | 11 | — | |
XMDLNBHGNQECLZ
|
9.1 | IC50 | 4 | — | |
CSYVEHWJTGNMOY
|
9.1 | Ki | 7 | — | |
HUNWQLBOLVYRMW
|
9.1 | IC50 | 11 | — | |
QXVWBJROURLRIW
|
9.1 | IC50 | 11 | — | |
AWLUUDKTCDEPGP
|
9.0 | Ki | 9 | — | |
BKCOGSHTNWTZNI
|
9.0 | IC50 | 15 | — | |
BRBJCJHJBAMBPR
|
9.0 | IC50 | 12 | — | |
IQFRBBNJBIHVDS
|
9.0 | IC50 | 4 | — | |
MOXBYMQBYZTOJA
|
9.0 | IC50 | 11 | — | |
STFCTZRFHURCAL
|
9.0 | IC50 | 4 | — | |
ODVRGHMGKSLOGS
|
8.9 | IC50 | 4 | — | |
WLPDYLPFPWPYBC
|
8.9 | IC50 | 11 | — | |
IAPISFUJUUDVNW
|
8.9 | IC50 | 15 | — | |
FOVGCCXTKLODIJ
|
8.8 | IC50 | 4 | — | |
ODDUUXAHBDCKIJ
|
8.8 | IC50 | 11 | — | |
PXUGMWMLQCLZNB
|
8.8 | IC50 | 2 | — | |
FSBMCTDYWXIBLM
|
8.8 | IC50 | 22 | — | |
JXJHPQHLHQTQQI
|
8.8 | IC50 | 15 | — | |
RZDGEHGGZJUCEA
|
8.7 | IC50 | 4 | — | |
GEQMDKKVXALFFX
|
8.7 | Ki | 9 | — | |
KFRGPUFONMCXQI
|
8.7 | IC50 | 11 | — | |
KJHOORCYJSBANN
|
8.7 | IC50 | 15 | — | |
XLSYZSRXVVCHLS
|
8.7 | IC50 | 48 | — | |
YGZQAQIWZFMADC
|
8.7 | IC50 | 12 | — | |
HKSZLNNOFSGOKW
|
8.7 | IC50 | 408 | — | |
MCZGHPQYRSSJLZ
|
8.7 | IC50 | 2 | — | |
QRPJDQZOXSLSEK
|
8.7 | IC50 | 11 | — | |
WIQLQHJLURUMAP
|
8.7 | IC50 | 9 | — | |
GGRVRRFOVWKWMD
|
8.6 | IC50 | 11 | — | |
GHNYLVIESIGHDJ
|
8.6 | IC50 | 9 | — | |
UAFDMWGGQQODTL
|
8.6 | Ki | 9 | — | |
VFVAQKKPFOPZEA
|
8.6 | IC50 | 2 | — | |
QBVOJALPYZEHOP
|
8.6 | Ki | 4 | — | |
XQVRYCHBRUAEMD
|
8.6 | IC50 | 2 | — | |
AAYPLLWGPJQWCC
|
8.5 | IC50 | 15 | Yes | |
CLCKDDAPJRHFEN
|
8.5 | IC50 | 9 | — | |
YRURITXEWXPMAI
|
8.5 | IC50 | 8 | Yes | |
YZVFJIYEYQIHIP
|
8.5 | IC50 | 15 | — | |
ZHMRPXZRUZLCNL
|
8.5 | IC50 | 8 | Yes |