Target Details
| UniProt AC | Q13557 |
|---|---|
| Gene Symbol | CAMK2D |
| Protein Name | Calcium/calmodulin-dependent protein kinase type II subunit delta |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF08332 (CaMKII_AD) PF00069 (Pkinase) |
Summary
- Multi-target molecules 150
- Clinical molecules 34
- Avg pChEMBL 6.76
KEGG Pathways (34)
- Adrenergic signaling in cardiomyocytes
- Aldosterone synthesis and secretion
- Amphetamine addiction
- Axon guidance
- Calcium signaling pathway
- Cholinergic synapse
- Circadian entrainment
- Cushing syndrome
- Diabetic cardiomyopathy
- Dopaminergic synapse
- Efferocytosis
- ErbB signaling pathway
- Gastric acid secretion
- Glioma
- Glucagon signaling pathway
- GnRH signaling pathway
- HIF-1 signaling pathway
- Inflammatory mediator regulation of TRP channels
- Insulin secretion
- Lipid and atherosclerosis
- Long-term potentiation
- Melanogenesis
- Necroptosis
- Neurotrophin signaling pathway
- Olfactory transduction
- Oocyte meiosis
- Oxytocin signaling pathway
- Parkinson disease
- Pathways in cancer
- Pathways of neurodegeneration - multiple diseases
- Proteoglycans in cancer
- Tuberculosis
- Wnt signaling pathway
- cAMP signaling pathway
Active Molecules (150)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
QUFBFSMDTSFORH
|
10.1 | IC50 | 2 | — | |
HKSZLNNOFSGOKW
|
9.5 | IC50 | 408 | — | |
HKSZLNNOFSGOKW
|
9.5 | Kd | 213 | — | |
NXSJMRCTGYTSTK
|
8.4 | Kd | 200 | — | |
UMTWTCVTRDYHQQ
|
8.3 | Ki | 56 | — | |
OSVUGUHRKMMBSE
|
8.2 | Kd | 170 | — | |
UZWDCWONPYILKI
|
8.2 | IC50 | 47 | — | |
MWKSRKSEWLRPBL
|
8.1 | Kd | 1075 | — | |
UIARLYUEJFELEN
|
8.1 | Kd | 289 | Yes | |
BPNUQXPIQBZCMR
|
8.0 | Ki | 60 | — | |
CHTMRWQLNNRRFJ
|
7.9 | Ki | 70 | — | |
BSFNGHCTZDCQBF
|
7.8 | Ki | 93 | — | |
YWTBGJGMTBHQTM
|
7.8 | Ki | 65 | — | |
OWRXHGAFWZFFCW
|
7.7 | Ki | 113 | — | |
ZCCPLJOKGAACRT
|
7.7 | Kd | 599 | — | |
KAJXOWFGKYKMMZ
|
7.6 | IC50 | 26 | Yes | |
LEJHMQJABOLACY
|
7.6 | IC50 | 9 | Yes | |
VXYDJXMHISGSDA
|
7.6 | Ki | 59 | — | |
WINHZLLDWRZWRT
|
7.6 | Ki | 66 | — | |
AILRADAXUVEEIR
|
7.5 | IC50 | 75 | — | |
KHGPYYFCIAISBU
|
7.5 | Ki | 31 | — | |
KSILWADEZRASEE
|
7.5 | IC50 | 4 | — | |
OAVGBZOFDPFGPJ
|
7.5 | Ki | 42 | Yes | |
BMGQWWVMWDBQGC
|
7.4 | Kd | 147 | Yes | |
BMGQWWVMWDBQGC
|
7.4 | Kd | 91 | Yes | |
NOVLXWHGKLXEJS
|
7.4 | IC50 | 4 | — | |
GDYZFFBMSBDTAA
|
7.4 | Ki | 60 | — | |
XPHWIERLJBFPFV
|
7.4 | Ki | 69 | — | |
APALQVMWCDGRJB
|
7.3 | IC50 | 9 | Yes | |
ZNEQEOGXKINPPR
|
7.3 | IC50 | 9 | Yes | |
LAMWYYXJYIQOQL
|
7.2 | IC50 | 16 | Yes | |
GPNZOTCLQNMQIC
|
7.2 | IC50 | 7 | Yes | |
FUMCKNCUEAQHCV
|
7.2 | Ki | 103 | — | |
PCQMERRARZKTPW
|
7.2 | Ki | 68 | — | |
DFMCXVONDDGQIY
|
7.1 | Ki | 66 | — | |
GCYXEGSPUDSZJY
|
7.1 | Ki | 82 | — | |
PSCJSWRVCKUMSL
|
7.1 | Ki | 35 | — | |
XFWUTMHVDGPWLH
|
7.1 | Ki | 75 | — | |
XOFQJBDORDALAH
|
7.1 | IC50 | 9 | Yes | |
ZPEBZVFGLUUCDX
|
7.1 | IC50 | 6 | — | |
HFNKQEVNSGCOJV
|
7.0 | Kd | 65 | — | |
WMUGNCAVDUVWIE
|
7.0 | IC50 | 9 | Yes | |
CHOKPCNUYFDUDO
|
7.0 | IC50 | 9 | Yes | |
BRGYPSBHCUNPNP
|
7.0 | IC50 | 9 | Yes | |
ZKLJKKASNXVQBZ
|
7.0 | Ki | 27 | — | |
MVJMMLFMPWITEJ
|
6.9 | Ki | 110 | — | |
WUBHCQHBUVGGRX
|
6.9 | Ki | 11 | — | |
ZGGIYFOLDBTZIL
|
6.9 | Ki | 27 | — | |
ARYNBWZQYLWGFJ
|
6.8 | IC50 | 2 | — | |
BNGOYHGMLMEWGU
|
6.8 | IC50 | 2 | — |