Target Details
| UniProt AC | Q13555 |
|---|---|
| Gene Symbol | CAMK2G |
| Protein Name | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF08332 (CaMKII_AD) PF00069 (Pkinase) |
Summary
- Multi-target molecules 123
- Clinical molecules 36
- Avg pChEMBL 6.78
KEGG Pathways (34)
- Adrenergic signaling in cardiomyocytes
- Aldosterone synthesis and secretion
- Amphetamine addiction
- Axon guidance
- Calcium signaling pathway
- Cholinergic synapse
- Circadian entrainment
- Cushing syndrome
- Diabetic cardiomyopathy
- Dopaminergic synapse
- Efferocytosis
- ErbB signaling pathway
- Gastric acid secretion
- Glioma
- Glucagon signaling pathway
- GnRH signaling pathway
- HIF-1 signaling pathway
- Inflammatory mediator regulation of TRP channels
- Insulin secretion
- Lipid and atherosclerosis
- Long-term potentiation
- Melanogenesis
- Necroptosis
- Neurotrophin signaling pathway
- Olfactory transduction
- Oocyte meiosis
- Oxytocin signaling pathway
- Parkinson disease
- Pathways in cancer
- Pathways of neurodegeneration - multiple diseases
- Proteoglycans in cancer
- Tuberculosis
- Wnt signaling pathway
- cAMP signaling pathway
Associated Diseases (1)
Active Molecules (123)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
LRINYHMQZRENCY
|
6.1 | Ki | 29 | — | |
OUJZYQBEFNDJQN
|
6.1 | Ki | 71 | — | |
OWDRQHVEJIYVOI
|
6.1 | Ki | 47 | — | |
PIQCTGMSNWUMAF
|
6.1 | Ki | 137 | Yes | |
RTDSHUGNRVXRHN
|
6.1 | Ki | 51 | — | |
TUJUZVJICDSNLY
|
6.1 | Ki | 19 | — | |
UYJNQQDJUOUFQJ
|
6.1 | Ki | 68 | — | |
WUWDLXZGHZSWQZ
|
6.1 | Ki | 41 | — | |
PBCZSGKMGDDXIJ
|
6.1 | Kd | 68 | Yes | |
BPNUQXPIQBZCMR
|
6.0 | Kd | 83 | Yes | |
ADQKGRUFGPUORP
|
6.0 | IC50 | 9 | Yes | |
NHHQJBCNYHBUSI
|
6.0 | Kd | 220 | — | |
BIIVYFLTOXDAOV
|
6.0 | Ki | 31 | — | |
CLRFYTGANQZOBS
|
6.0 | Ki | 41 | — | |
GMZCYCKIXQZORP
|
6.0 | IC50 | 6 | — | |
IVVSBEQDCAZLFY
|
6.0 | IC50 | 333 | — | |
PDBPUXLUVDSLML
|
6.0 | Ki | 14 | — | |
RZJKNYACYSIBFY
|
6.0 | IC50 | 4 | — | |
VBUWAJWPXASNGM
|
6.0 | Ki | 9 | — | |
VNGYQBMDQMDALH
|
6.0 | Ki | 25 | — | |
XJSFDMGICAWQFS
|
6.0 | Ki | 60 | — | |
ZVWRFVCNQOECJS
|
6.0 | Ki | 71 | — | |
ZWVZORIKUNOTCS
|
6.0 | Ki | 69 | — |