Target Details
| UniProt AC | Q13490 |
|---|---|
| Gene Symbol | BIRC2 |
| Protein Name | Baculoviral IAP repeat-containing protein 2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00653 (BIR) PF00619 (CARD) PF21290 (UBA_BIRC2-3) PF13920 (zf-C3HC4_3) |
Summary
- Multi-target molecules 876
- Clinical molecules 0
- Avg pChEMBL 7.55
KEGG Pathways (16)
- Apoptosis
- Apoptosis - multiple species
- Focal adhesion
- Herpes simplex virus 1 infection
- Hippo signaling pathway
- NF-kappa B signaling pathway
- NOD-like receptor signaling pathway
- Necroptosis
- Pathways in cancer
- Platinum drug resistance
- Salmonella infection
- Small cell lung cancer
- TNF signaling pathway
- Toxoplasmosis
- Transcriptional misregulation in cancer
- Ubiquitin mediated proteolysis
Active Molecules (876)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GQJBERRGZSKOOZ
|
7.8 | IC50 | 2 | — | |
WLMCRYCCYXHPQF
|
7.8 | IC50 | 3 | — | |
YJLHAVCBMPSMFN
|
7.8 | IC50 | 3 | — | |
AIXVXKVHWSPNEC
|
7.8 | IC50 | 3 | — | |
ALTYAOOJIAHVSY
|
7.8 | IC50 | 3 | — | |
AQYZQNSXTYWHPV
|
7.8 | IC50 | 3 | — | |
AVYFDPBYGWKKBG
|
7.8 | IC50 | 3 | — | |
BIFVOPZOTHTOGF
|
7.8 | IC50 | 3 | — | |
BRQBWMHJPZSZEQ
|
7.8 | IC50 | 3 | — | |
DCCKHDGXWFCIQA
|
7.8 | IC50 | 3 | — | |
DIWNDODJEWHRMK
|
7.8 | IC50 | 3 | — | |
FEOQMFDTJIBXJN
|
7.8 | IC50 | 3 | — | |
HGRHVARSRKKSKF
|
7.8 | IC50 | 3 | — | |
HIXDQGDGQOLXPP
|
7.8 | IC50 | 3 | — | |
HNNQKZCYDVGGMV
|
7.8 | IC50 | 3 | — | |
HRCWDZAISKKZAO
|
7.8 | IC50 | 3 | — | |
IRVKITYLCGOXFW
|
7.8 | IC50 | 2 | — | |
ITEZCVDAENPOBN
|
7.8 | IC50 | 3 | — | |
JCVHHNXHTOUAGW
|
7.8 | IC50 | 3 | — | |
JMPRLWFAISUPIX
|
7.8 | IC50 | 3 | — | |
JOLPINQANFDBCZ
|
7.8 | IC50 | 3 | — | |
JUIWWZNZWKMFLN
|
7.8 | IC50 | 3 | — | |
KCMBUTPQNTUBNW
|
7.8 | IC50 | 3 | — | |
LFXYGPIYHBAVFI
|
7.8 | IC50 | 3 | — | |
LJUIMXKMJHTWQX
|
7.8 | IC50 | 3 | — | |
MDHCDJRSCGPLNK
|
7.8 | IC50 | 3 | — | |
MVWURGXHGZJSJK
|
7.8 | IC50 | 3 | — | |
MYOKHRUTGIGVCF
|
7.8 | IC50 | 3 | — | |
MYOKHRUTGIGVCF
|
7.8 | IC50 | 3 | — | |
OJBPFHAKRFAWQQ
|
7.8 | IC50 | 3 | — | |
OLGJFBOHTVNVPD
|
7.8 | IC50 | 3 | — | |
ORJAOIJIYHRTCD
|
7.8 | IC50 | 2 | — | |
OZPYMCZSAXSADS
|
7.8 | IC50 | 3 | — | |
PKWPITDONSHTTD
|
7.8 | IC50 | 3 | — | |
PPPOFDUCCMFIKK
|
7.8 | IC50 | 3 | — | |
QAKRFBAGPGVJHN
|
7.8 | IC50 | 3 | — | |
QEZFQIOHOJJHSC
|
7.8 | IC50 | 3 | — | |
QYCXIAFJNYULJD
|
7.8 | IC50 | 3 | — | |
RHXHYBSZLSDNRG
|
7.8 | IC50 | 3 | — | |
RNSORXGIOFJAQP
|
7.8 | IC50 | 3 | — | |
RVLJJVXFQZBCEB
|
7.8 | IC50 | 3 | — | |
SDZIYSRRRZJHSH
|
7.8 | IC50 | 3 | — | |
SFRBIHGATTUURB
|
7.8 | IC50 | 2 | — | |
SRAMQAQKHPYBIT
|
7.8 | IC50 | 3 | — | |
SZFVPADHXNZNET
|
7.8 | IC50 | 3 | — | |
UZMIPDVOAWRTQZ
|
7.8 | IC50 | 3 | — | |
WDDBSLKKOUVEOO
|
7.8 | IC50 | 3 | — | |
WIJHEGBFHICBBP
|
7.8 | IC50 | 3 | — | |
WPIVZRMUOWEPNG
|
7.8 | IC50 | 3 | — | |
WQTMCRLCLZFGGS
|
7.8 | IC50 | 3 | — |