Target Details
UniProt ACQ13464
Gene SymbolROCK1
Protein NameRho-associated protein kinase 1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF25346 (PH_MRCK) PF00069 (Pkinase) PF08912 (Rho_Binding)
UniProt
Summary
  • Multi-target molecules 1,614
  • Clinical molecules 34
  • Avg pChEMBL 7.13
KEGG Pathways (22)
Top Co-occurrence Targets
Active Molecules (1,614)
InChIKey pChEMBL Type Targets Clinical
FCKYQPCANANIBR 7.2 IC50 2 —
LRNKGINCBWKQIS 7.2 IC50 2 —
LRNKGINCBWKQIS 7.2 IC50 2 —
NMHHYBNZLFASKW 7.2 IC50 2 —
OQWZIAVXCYIZNN 7.2 IC50 2 —
PDSLHUWAGNRMJH 7.2 IC50 2 —
UIARLYUEJFELEN 7.2 Kd 289 Yes
ZEBTVUQBWJLGIO 7.2 IC50 2 —
ASPDMKGCEMLVBM 7.2 IC50 2 —
AXHOMFNSCRXCJW 7.2 IC50 2 —
CTYNRQDSJJAZAV 7.2 IC50 2 —
CYLSXYAMTHBWRF 7.2 Ki 4 —
FNAPEKSJRDLQRC 7.2 Ki 4 —
GQMCGRYPKMDMGV 7.2 IC50 2 —
HSRYETVWRVWJQQ 7.2 IC50 6 —
NLDHEYLJTMKCDH 7.2 IC50 2 —
RCDCKDSJQMZVKX 7.2 IC50 2 —
ULONQWNHVOAFTO 7.2 Ki 2 —
VTSLKIKDRBEGHX 7.2 Ki 4 —
HWGXVQXOZZVGKP 7.2 Ki 3 —
LZKXNZXRQFFQAH 7.2 IC50 3 —
ZIIWGJMMDJWIKB 7.2 IC50 7 —
GPXKVULNYYNGDP 7.2 IC50 4 —
HFNKQEVNSGCOJV 7.2 Kd 65 —
MCBPNFWHHNJTGN 7.2 IC50 5 —
OQORIVHBMBWOAH 7.2 IC50 2 —
QSWXBXSDEQWIGI 7.2 IC50 2 —
YOVPXCVUQRNYHG 7.2 Ki 2 —
LSMZQWHWUVFUIF 7.2 IC50 2 —
QAJSUJQESOQFHQ 7.2 IC50 2 —
ZDTUVVAJVVQVOT 7.2 IC50 4 —
BQYDGSNDLAZAEW 7.2 Ki 13 —
FAUXLGJPBACBAU 7.2 IC50 2 —
JJSJCFRALYFXHF 7.2 IC50 2 —
JZTOUVBEZONDKA 7.2 Ki 80 —
LDADEKXOFGQCIZ 7.2 IC50 2 —
NFKMFNBKEOQNPZ 7.2 Ki 43 —
VSVKFEMFAYXZKR 7.2 Ki 14 Yes
YXAYEZQYTJGWNT 7.2 IC50 2 —
ZCZCMEBFKRXYRT 7.2 IC50 2 —
BUHHYYUWCDSWAP 7.2 IC50 2 —
FLZNZODFDWZMJE 7.2 IC50 2 —
HCJBFYQKXGZALI 7.2 IC50 2 —
MFYBDDIXWJAHOA 7.2 IC50 2 —
RACINMWWYRFJNX 7.2 IC50 2 —
SVEDSLIXPDIZCB 7.2 IC50 2 —
SXDPQGRNHSLZPC 7.2 IC50 18 —
TXBFBOHWKUHOLB 7.2 IC50 2 —
UGWBCYQPCXKMGF 7.2 IC50 2 —
UHJHCLYQRUAKGN 7.2 IC50 2 —
2D structure