Target Details
| UniProt AC | Q13237 |
|---|---|
| Gene Symbol | PRKG2 |
| Protein Name | cGMP-dependent protein kinase 2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00027 (cNMP_binding) PF00069 (Pkinase) |
Summary
- Multi-target molecules 91
- Clinical molecules 8
- Avg pChEMBL 6.8
KEGG Pathways (11)
Associated Diseases (2)
Active Molecules (91)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MLGGUGPIWDHBAI
|
8.6 | IC50 | 10 | — | |
MLGGUGPIWDHBAI
|
8.6 | Ki | 33 | — | |
KGPGFQWBCSZGEL
|
8.5 | Kd | 59 | Yes | |
BSFNGHCTZDCQBF
|
8.4 | Ki | 93 | — | |
VGNKOJURPOHWJF
|
8.4 | Ki | 21 | — | |
CHTMRWQLNNRRFJ
|
8.1 | Ki | 70 | — | |
NJPWCTYVEJIQBM
|
7.9 | Ki | 72 | — | |
HKSZLNNOFSGOKW
|
7.8 | IC50 | 408 | — | |
JRVSFZKYQCETAH
|
7.8 | Ki | 19 | — | |
BPNUQXPIQBZCMR
|
7.7 | Kd | 83 | Yes | |
LRZYYIZFBXFSJB
|
7.7 | Ki | 69 | — | |
PFCUZXCHLYIMTJ
|
7.7 | Ki | 18 | — | |
ZRTWUBWXIGHVET
|
7.7 | Ki | 10 | — | |
XBFAFSAUQFDEOK
|
7.6 | IC50 | 5 | — | |
CALAEFSQWBJMDU
|
7.6 | Ki | 21 | — | |
UIARLYUEJFELEN
|
7.6 | Kd | 289 | Yes | |
VXYDJXMHISGSDA
|
7.6 | Ki | 59 | — | |
HNXJWWRRSGDVIW
|
7.5 | Ki | 13 | — | |
UMTWTCVTRDYHQQ
|
7.5 | Ki | 56 | — | |
IEDDDZFQZKDRBJ
|
7.5 | IC50 | 9 | — | |
DYSRECIVMDGUQU
|
7.4 | Ki | 29 | — | |
MTYMWGNJKDHWGN
|
7.4 | Ki | 18 | — | |
NEWAULHLLUCDPD
|
7.4 | Ki | 27 | — | |
XYZNKCSDQRKAFR
|
7.4 | Ki | 53 | — | |
YOVNFNXUCOWYSG
|
7.4 | Ki | 33 | Yes | |
OSVUGUHRKMMBSE
|
7.4 | Kd | 170 | — | |
YGEACCLUBSGMMJ
|
7.3 | Ki | 16 | — | |
YPJJSXBVVGPFHA
|
7.3 | Ki | 18 | — | |
ZRQXCQXWTLVASO
|
7.3 | Ki | 36 | — | |
NXSJMRCTGYTSTK
|
7.2 | Kd | 200 | — | |
BMGQWWVMWDBQGC
|
7.1 | Kd | 147 | Yes | |
DKXHSOUZPMHNIZ
|
7.1 | Ki | 51 | Yes | |
ZCXXFPLQFFRMPN
|
7.1 | Ki | 12 | — | |
SGHXFHRRWFLILP
|
7.0 | Ki | 29 | — | |
CHQYAWLKOUOTQO
|
6.9 | IC50 | 20 | — | |
XMFUGSRATNLPRM
|
6.9 | Ki | 19 | — | |
DFMCXVONDDGQIY
|
6.8 | Ki | 66 | — | |
HXDDWVMJYDULAZ
|
6.8 | Ki | 13 | — | |
OHPRWVPOPFGLJG
|
6.8 | Ki | 19 | — | |
VAMDLIMJLAPZGX
|
6.8 | Ki | 10 | — | |
AXRCEOKUDYDWLF
|
6.8 | Kd | 31 | — | |
AOBLBPWPSKBHSI
|
6.7 | Ki | 55 | — | |
DPPIQOOVRLCHQC
|
6.7 | Ki | 6 | — | |
QQWUGDVOUVUTOY
|
6.6 | Kd | 231 | Yes | |
SHENEEFOURUIBP
|
6.6 | Ki | 29 | — | |
GCYXEGSPUDSZJY
|
6.5 | Ki | 82 | — | |
KWRXWPRFIUJQBP
|
6.5 | Ki | 25 | — | |
NPLQZQGAZAUUTB
|
6.5 | Ki | 9 | — | |
NRSGWEVTVGZDFC
|
6.5 | Ki | 50 | — | |
XSRHBCYNCKAFKS
|
6.5 | Ki | 45 | — |