Target Details
| UniProt AC | Q13153 |
|---|---|
| Gene Symbol | PAK1 |
| Protein Name | Serine/threonine-protein kinase PAK 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00786 (PBD) PF00069 (Pkinase) |
Summary
- Multi-target molecules 107
- Clinical molecules 6
- Avg pChEMBL 7.25
KEGG Pathways (20)
- Axon guidance
- C-type lectin receptor signaling pathway
- Chemokine signaling pathway
- Epithelial cell signaling in Helicobacter pylori infection
- ErbB signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Hippo signaling pathway - multiple species
- Human immunodeficiency virus 1 infection
- IgSF CAM signaling
- MAPK signaling pathway
- Natural killer cell mediated cytotoxicity
- Pathogenic Escherichia coli infection
- Proteoglycans in cancer
- Ras signaling pathway
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- Salmonella infection
- T cell receptor signaling pathway
- cAMP signaling pathway
Associated Diseases (1)