NR1H3 — MultiTargetDB

Target Details

UniProt AC	`Q13133`
Gene Symbol	NR1H3
Protein Name	Oxysterols receptor LXR-alpha
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00104 (Hormone_recep) PF00105 (zf-C4)

Summary

Multi-target molecules 422
Clinical molecules 0
Avg pChEMBL 7.18

KEGG Pathways (5)

Top Co-occurrence Targets

NR1H2 420 shared
RXRA 34 shared
PPARD 12 shared
PPARA 9 shared
PPARG 7 shared
CYP2C9 3 shared
RORC 1 shared
RORA 1 shared
NR3C1 1 shared
NR1I2 1 shared

Active Molecules (422)

InChIKey	pChEMBL	Type	Targets	Clinical
`AORBCLGGYNFMGN`	7.7	IC50	4	—
`WRGYDZSMTYBYJC`	7.7	IC50	2	—
`DDVQRICMCZPTNJ`	7.7	IC50	2	—
`KMTFPMRUPSWRTQ`	7.7	Ki	3	—
`LBPQARCLPTVEGQ`	7.7	IC50	2	—
`WZQNVHXAZPMTQI`	7.7	Ki	2	—
`FVKYONNSLLCHIF`	7.7	IC50	2	—
`LFYZXWABUGTSOT`	7.7	IC50	2	—
`UUIQBDLORYXQJP`	7.7	IC50	2	—
`YPXOOPFXOOABHI`	7.7	IC50	2	—
`VSLBVBOGQLFVOY`	7.7	Ki	2	—
`IAVNBGWOUPTSOV`	7.6	IC50	2	—
`XDSUZROBCUROQA`	7.6	IC50	2	—
`MVEYCHUAHRZQOD`	7.6	Ki	3	—
`UWFHFVAFWATDDO`	7.6	IC50	2	—
`YTEDTWJJQBCOTI`	7.6	Ki	2	—
`HNBMEVGNLQVKHO`	7.6	IC50	2	—
`NLDOCDWHNYIGKV`	7.6	IC50	2	—
`SWBBNSPWRVCYAE`	7.6	Ki	3	—
`YXXFEOBGLYBWLG`	7.6	Ki	2	—
`IQRSIUBKAADOQA`	7.6	Ki	2	—
`KZCSVWPMPDGZGU`	7.5	Ki	2	—
`DUOZJJLSLMAQCI`	7.5	IC50	2	—
`DYTISOKVYHWYCW`	7.5	IC50	2	—
`GRHBEGZXUDYQLG`	7.5	IC50	2	—
`XBWKFFVZKTYRJE`	7.5	IC50	2	—
`NVCNWULYEHGNKG`	7.5	IC50	2	—
`VVVMBZVHNIYCQS`	7.5	Ki	3	—
`BKOKGTVPLDCTIS`	7.5	Ki	2	—
`IGGSXCWSHVYVMA`	7.5	Ki	2	—
`NEGSIYPKPKVQAA`	7.5	Ki	2	—
`QIFYDQQBXMOQLW`	7.5	IC50	2	—
`CGUCJIOARZYDCJ`	7.5	IC50	2	—
`OVYOPGSHTATUOV`	7.5	Ki	2	—
`TXKFTWAELLNECY`	7.5	IC50	2	—
`ITROVDJOIPDCOB`	7.5	IC50	2	—
`JLWYCHMJOLWTSZ`	7.5	IC50	2	—
`JNGMQNSQSCYLSD`	7.5	IC50	2	—
`TUYZXSLKXBNYSH`	7.5	IC50	2	—
`TZBRFAASYWFUGK`	7.5	IC50	5	—
`HNAJDMYOTDNOBK`	7.4	IC50	3	—
`WZMZHHPXANSLBG`	7.4	Ki	3	—
`YRWXCMJJJAVQPM`	7.4	IC50	2	—
`LODWYHGIAQYCAL`	7.4	Ki	3	—
`YJTSPUKQCBSIGP`	7.4	IC50	2	—
`FAYRZYDHLUVKKC`	7.4	IC50	5	—
`MMFGEAJCSXYUPB`	7.4	Ki	2	—
`OCSBWUNDZQJSRW`	7.4	Ki	2	—
`CNVKZYLQZYULJV`	7.4	IC50	2	—
`CRRQUBDXEDTMJH`	7.4	Ki	2	—