Target Details
| UniProt AC | Q12852 |
|---|---|
| Gene Symbol | MAP3K12 |
| Protein Name | Mitogen-activated protein kinase kinase kinase 12 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF07714 (PK_Tyr_Ser-Thr) |
Summary
- Multi-target molecules 54
- Clinical molecules 8
- Avg pChEMBL 7.47
KEGG Pathways (1)
Active Molecules (54)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
UIARLYUEJFELEN
|
6.1 | Kd | 289 | Yes | |
IVVSBEQDCAZLFY
|
6.0 | IC50 | 333 | — | |
KHVVJKLNKLQLJZ
|
6.0 | IC50 | 288 | — | |
MAHFVAHPQSLLJF
|
6.0 | IC50 | 288 | — |