Target Details
UniProt ACQ08881
Gene SymbolITK
Protein NameTyrosine-protein kinase ITK/TSK
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00779 (BTK) PF00169 (PH) PF07714 (PK_Tyr_Ser-Thr) PF00017 (SH2) PF00018 (SH3_1)
UniProt
Summary
  • Multi-target molecules 676
  • Clinical molecules 27
  • Avg pChEMBL 7.57
KEGG Pathways (3)
Associated Diseases (2)
Top Co-occurrence Targets
Active Molecules (676)
InChIKey pChEMBL Type Targets Clinical
AZFYXBXDTZLJGD 7.3 IC50 2 —
BJONHSCXBJYULE 7.3 IC50 2 —
DHVUCAZYIPVMMP 7.3 IC50 2 —
DPQGUVILZRVONN 7.3 IC50 2 —
GFHRYXHUBXMQGZ 7.3 IC50 2 —
GKTXWXUJRPJCHX 7.3 IC50 2 —
GLWSNYDQJONZIV 7.3 IC50 2 —
HJPYZEYSJLAFFW 7.3 IC50 2 —
HPNFGOZTUMHEJM 7.3 IC50 2 —
IPPHYKLDCJQTJI 7.3 IC50 2 —
IZOQLNVGRPSGOU 7.3 IC50 3 —
JDXHHQVVORDEDG 7.3 IC50 2 —
JLGAHHJQXBLBSK 7.3 IC50 2 —
JPZSBNNZGWBSEB 7.3 IC50 2 —
KFXNBEFHAHIVDG 7.3 IC50 2 —
KNYIIZLUSZJWSL 7.3 IC50 2 —
KXBDTLQSDKGAEB 7.3 IC50 8 —
LVQDMCXIIKGTTL 7.3 IC50 2 —
MBQOLZKCWIMGNL 7.3 IC50 2 —
NFSNTHIPBLRXCV 7.3 IC50 2 —
NRCNNNKRVGICGY 7.3 IC50 2 —
OOPSGLUITPSZOK 7.3 IC50 2 —
PCTROZXOUFGQPK 7.3 IC50 2 —
QCJXKESYOASOES 7.3 IC50 2 —
SBOPEFHTOFMNSD 7.3 IC50 2 —
SPSAUHMKIJCTCP 7.3 IC50 2 —
TUHXUKDYTKWTGG 7.3 IC50 2 —
TUHXUKDYTKWTGG 7.3 IC50 2 —
TXORKGYZMUSRKS 7.3 IC50 2 —
UMBDWDIRLTVPBF 7.3 IC50 9 —
UNPGABFQHYGLOJ 7.3 IC50 2 —
UOJJIRQZYSCCEU 7.3 IC50 3 —
UQPCMSBCSBHRAK 7.3 IC50 3 —
UXHFWCLHWKJMNI 7.3 IC50 2 —
VDUDICQYCWGKOX 7.3 IC50 2 —
VNDKDRXYEXEKGQ 7.3 IC50 2 —
VPIIYIKGMZOSMS 7.3 IC50 2 —
VVLHQJDAUIPZFH 7.3 IC50 3 —
VZXXRAOOPZBUJW 7.3 IC50 2 —
VZXXRAOOPZBUJW 7.3 IC50 2 —
WQDMXYSIBUJDCH 7.3 IC50 2 —
WXSQRASGXQJANS 7.3 IC50 2 —
WXSQRASGXQJANS 7.3 IC50 2 —
XBOASQDXYQLAHV 7.3 IC50 2 —
XCWNPLBYOKTWMD 7.3 IC50 2 —
XMTMZIVGULRXHT 7.3 IC50 2 —
XMXULPDQKZIBID 7.3 IC50 2 —
XQRHDEQLYAPLAK 7.3 IC50 2 —
XZRLUFDHKLBOSM 7.3 IC50 2 —
YBESIBQNBNKGKU 7.3 IC50 2 —
2D structure