Target Details
| UniProt AC | Q07889 |
|---|---|
| Gene Symbol | SOS1 |
| Protein Name | Son of sevenless homolog 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00617 (RasGEF) PF00618 (RasGEF_N) PF00621 (RhoGEF) PF22697 (SOS1_NGEF_PH) |
Summary
- Multi-target molecules 766
- Clinical molecules 0
- Avg pChEMBL 8.12
KEGG Pathways (48)
- Acute myeloid leukemia
- Alcoholism
- B cell receptor signaling pathway
- Breast cancer
- Chemical carcinogenesis - reactive oxygen species
- Chemical carcinogenesis - receptor activation
- Chemokine signaling pathway
- Choline metabolism in cancer
- Chronic myeloid leukemia
- Colorectal cancer
- EGFR tyrosine kinase inhibitor resistance
- Endocrine resistance
- Endometrial cancer
- ErbB signaling pathway
- Estrogen signaling pathway
- Fc epsilon RI signaling pathway
- Focal adhesion
- FoxO signaling pathway
- Gap junction
- Gastric cancer
- Glioma
- GnRH signaling pathway
- Growth hormone synthesis, secretion and action
- Hepatitis B
- Hepatitis C
- Hepatocellular carcinoma
- Human cytomegalovirus infection
- Human papillomavirus infection
- Insulin signaling pathway
- JAK-STAT signaling pathway
- MAPK signaling pathway
- MicroRNAs in cancer
- Natural killer cell mediated cytotoxicity
- Neurotrophin signaling pathway
- Non-small cell lung cancer
- PI3K-Akt signaling pathway
- Pathways in cancer
- Phospholipase D signaling pathway
- Prolactin signaling pathway
- Prostate cancer
- Proteoglycans in cancer
- Ras signaling pathway
- Regulation of actin cytoskeleton
- Relaxin signaling pathway
- Renal cell carcinoma
- T cell receptor signaling pathway
- Thermogenesis
- mTOR signaling pathway
Associated Diseases (3)