CHRNE — MultiTargetDB

Target Details

UniProt AC	`Q04844`
Gene Symbol	CHRNE
Protein Name	Acetylcholine receptor subunit epsilon
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF02931 (Neur_chan_LBD) PF02932 (Neur_chan_memb)

Summary

Multi-target molecules 10
Clinical molecules 0
Avg pChEMBL 7.31

KEGG Pathways (1)

Neuroactive ligand-receptor interaction

Associated Diseases (1)

Congenital myasthenic syndrome

Top Co-occurrence Targets

BCHE 9 shared
ACHE 2 shared
HRH3 1 shared
CHRNA9 1 shared
CHRNA10 1 shared
SIGMAR1 1 shared
CHRNA6 1 shared
KCNH2 1 shared
CHRND 1 shared
CHRNB3 1 shared

Active Molecules (10)

InChIKey	pChEMBL	Type	Targets	Clinical
`UDWFAMFUCBSKHI`	8.2	IC50	2	—
`XMGXMSRQJGXDFY`	7.6	IC50	2	—
`ADEBPBSSDYVVLD`	7.5	IC50	8	—
`UUXGUHRRRWGLJM`	7.3	IC50	2	—
`VXOMGIIQSPHLCF`	7.2	IC50	2	—
`FNFARHRRHGLYQK`	7.2	IC50	2	—
`YLJREFDVOIBQDA`	7.1	IC50	7	—
`GOJHKUQOTUCVQG`	7.1	IC50	2	—
`MEJIZAOYTQIGPW`	7.0	IC50	2	—
`XFBDKMSGGGCNAI`	6.9	IC50	11	—