Target Details
| UniProt AC | Q00535 |
|---|---|
| Gene Symbol | CDK5 |
| Protein Name | Cyclin-dependent kinase 5 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) |
Summary
- Multi-target molecules 1,218
- Clinical molecules 62
- Avg pChEMBL 6.94
KEGG Pathways (4)
Associated Diseases (1)
Active Molecules (1,218)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MRPGRAKIAJJGMM
|
6.7 | IC50 | 11 | — | |
WLTRIWCDHOZNRP
|
6.7 | IC50 | 14 | — | |
ZXOPGTSQJRRYHF
|
6.7 | IC50 | 4 | — | |
JPOSFPUHBHRUAX
|
6.7 | IC50 | 40 | Yes | |
RRLCIPKWWCUBQQ
|
6.7 | IC50 | 2 | — | |
WQGCPJJNZKLUAU
|
6.7 | IC50 | 4 | — | |
WQQWVDYMAJEXGG
|
6.7 | IC50 | 6 | — | |
WEQRXDXDFLBIDK
|
6.7 | IC50 | 8 | — | |
XCGFQIAYNVIMQG
|
6.7 | IC50 | 2 | — | |
YPYJVFNIAPNHKS
|
6.7 | IC50 | 2 | — | |
DYJRMFLPJIIEQG
|
6.7 | IC50 | 2 | — | |
HOCBJBNQIQQQGT
|
6.7 | IC50 | 10 | — | |
CFWHZRPUZQMMGO
|
6.6 | IC50 | 2 | — | |
DTBMYSHZPNXMDE
|
6.6 | IC50 | 8 | Yes | |
HFEVNTGRPXCJIM
|
6.6 | IC50 | 6 | — | |
IGQSMAAWNDBZSW
|
6.6 | IC50 | 5 | — | |
QJAWGKGRUPQRDX
|
6.6 | IC50 | 2 | — | |
WNAJERRQHPZRPG
|
6.6 | IC50 | 3 | — | |
JGCUIZCYQPBQHU
|
6.6 | IC50 | 2 | — | |
PFRMQZGBTCACGO
|
6.6 | IC50 | 7 | — | |
DSMBDRWDECFDNR
|
6.6 | IC50 | 6 | — | |
FHBXTMDDIRIZEX
|
6.6 | IC50 | 2 | — | |
LAKIWNNGQWULBU
|
6.6 | IC50 | 2 | — | |
ULYHZZIABNHYBC
|
6.6 | IC50 | 2 | — | |
VPHIIYUPZXTLRL
|
6.6 | IC50 | 2 | — | |
VYIRYOGIKCRYCM
|
6.6 | IC50 | 2 | — | |
XVUWYNOULLGRIG
|
6.6 | IC50 | 2 | — | |
CGBSYSRPJXLGPT
|
6.6 | IC50 | 2 | — | |
DTDADKQWIZRVSD
|
6.6 | IC50 | 2 | — | |
HEVBCYZPXGZFGS
|
6.6 | IC50 | 11 | — | |
HPRKAXQQWJSFBW
|
6.6 | IC50 | 2 | — | |
CXLWAPHHTVIISB
|
6.6 | IC50 | 2 | — | |
DKZYXHCYPUVGAF
|
6.6 | Kd | 112 | — | |
FIKVDYWIFLBJSG
|
6.6 | IC50 | 3 | — | |
GDYZFFBMSBDTAA
|
6.6 | Ki | 60 | — | |
GHAZVJQMLWOQLP
|
6.6 | Ki | 17 | — | |
GUMBHNMWKMFKRT
|
6.6 | Ki | 23 | — | |
IFQICUARAXVEIQ
|
6.6 | Ki | 18 | — | |
IRJVSHBVCRPYII
|
6.6 | IC50 | 4 | — | |
OADRBDVURCEKRP
|
6.6 | Ki | 44 | — | |
VVEGARMQKNYDID
|
6.6 | Ki | 24 | — | |
WHYNIAPMAFAUQX
|
6.6 | IC50 | 2 | — | |
WZISGNDZZPSYRP
|
6.6 | Ki | 20 | — | |
ZSDNXKRZKUHCBB
|
6.6 | IC50 | 2 | — | |
LSBBZCLDJSCTQA
|
6.6 | IC50 | 2 | — | |
SCFMWQIQBVZOQR
|
6.6 | IC50 | 14 | Yes | |
BHAXWZYPXSKKNS
|
6.6 | IC50 | 2 | — | |
IMQYKFJIPMIFGC
|
6.6 | IC50 | 2 | — | |
OCDOLYOYOWZOEQ
|
6.6 | IC50 | 2 | — | |
QACRRBHRACNFKC
|
6.6 | IC50 | 2 | — |