Target Details
| UniProt AC | Q00534 |
|---|---|
| Gene Symbol | CDK6 |
| Protein Name | Cyclin-dependent kinase 6 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) |
Summary
- Multi-target molecules 1,915
- Clinical molecules 17
- Avg pChEMBL 7.56
KEGG Pathways (23)
- Breast cancer
- Cell cycle
- Cellular senescence
- Chronic myeloid leukemia
- Cushing syndrome
- Epstein-Barr virus infection
- Glioma
- Hepatitis C
- Hepatocellular carcinoma
- Human cytomegalovirus infection
- Human papillomavirus infection
- Influenza A
- Kaposi sarcoma-associated herpesvirus infection
- Measles
- Melanoma
- MicroRNAs in cancer
- Non-small cell lung cancer
- PI3K-Akt signaling pathway
- Pancreatic cancer
- Pathways in cancer
- Small cell lung cancer
- Viral carcinogenesis
- p53 signaling pathway
Associated Diseases (1)
Active Molecules (1,915)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
WTDHONKZUZNMOZ
|
6.0 | IC50 | 6 | — | |
YJGKHEQGTLAYHU
|
6.0 | IC50 | 9 | — | |
YTDAMDXDSPIYMI
|
6.0 | IC50 | 5 | — | |
FRVRHBOJYYGHIN
|
6.0 | IC50 | 2 | — | |
GLMXGXBRXJVWPG
|
6.0 | IC50 | 2 | — | |
PLCXKWHEWFSTBP
|
6.0 | IC50 | 2 | — | |
AIOFXERAXQYANK
|
6.0 | IC50 | 9 | — | |
VSTRBHWJZOVRDC
|
6.0 | IC50 | 4 | — | |
PCDQTEDODXVPNZ
|
6.0 | IC50 | 2 | — | |
IVVSBEQDCAZLFY
|
6.0 | IC50 | 333 | — | |
KHVVJKLNKLQLJZ
|
6.0 | IC50 | 288 | — | |
MAHFVAHPQSLLJF
|
6.0 | IC50 | 288 | — | |
VQYVGPOQLCWPID
|
6.0 | IC50 | 4 | — | |
WDUJNJVDMCCIOO
|
6.0 | IC50 | 2 | — | |
WYBDIAZRTPZHAJ
|
6.0 | IC50 | 6 | — |