Target Details
| UniProt AC | P78417 |
|---|---|
| Gene Symbol | GSTO1 |
| Protein Name | Glutathione S-transferase omega-1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF14497 (GST_C_3) PF13409 (GST_N_2) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 6.93
KEGG Pathways (12)
- Chemical carcinogenesis - DNA adducts
- Chemical carcinogenesis - reactive oxygen species
- Chemical carcinogenesis - receptor activation
- Drug metabolism - cytochrome P450
- Drug metabolism - other enzymes
- Fluid shear stress and atherosclerosis
- Glutathione metabolism
- Hepatocellular carcinoma
- Metabolic pathways
- Metabolism of xenobiotics by cytochrome P450
- Pathways in cancer
- Platinum drug resistance
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
7.0 | Kd | 1075 | — | |
BLMPQMFVWMYDKT
|
6.8 | IC50 | 43 | — |